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接受长期阿片类药物治疗的慢性疼痛患者的营养与饮食行为

Nutrition and eating behavior in patients with chronic pain receiving long-term opioid therapy.

作者信息

Meleger Alec L, Froude Cameron Kiely, Walker Joseph

机构信息

Department of Physical Medicine and Rehabilitation, Harvard Medical School, Boston; and Spaulding Rehabilitation Hospital, 101 Main St, Suite 101, Medford, MA 02155(∗).

Marriage and Family Therapy Program, Human Development and Family Studies, University of Connecticut, Storrs CT(†).

出版信息

PM R. 2014 Jan;6(1):7-12.e1. doi: 10.1016/j.pmrj.2013.08.597. Epub 2013 Aug 22.

Abstract

OBJECTIVE

To assess eating behavior and nutrient intake in a group of patients who were diagnosed with chronic pain and received long-term opioid analgesic therapy.

DESIGN

A descriptive, exploratory study with a convenience sample.

SETTING

An outpatient pain rehabilitation center.

PARTICIPANTS

Patients diagnosed with chronic pain who received long-term opioid analgesic therapy (N = 50).

MAIN OUTCOME MEASUREMENTS

Body mass index, the Food Frequency Questionnaire developed by the Nutrition Assessment Shared Resource of Fred Hutchinson Cancer Research Center, and the Eating Behavior Inventory.

RESULTS

Of 50 participants, 14 (28%) and 22 (44%) were found to be overweight and obese, respectively. Mean (±SD) daily caloric intake (kcal) was 2008.5 ± 926.0 among men and 1694.8 ± 672.4 among women. Daily mean (±SD) consumption of fruit and vegetable servings, calculated with the summation method, was found to be 1.8 ± 1.1 and 1.9 ± 1.5, respectively. Our patient sample showed the following mean (±SD) daily intake of the following substances: added sugars (g), 74.4 ± 43.0; fiber (g), 17.3 ± 7.5; cholesterol (mg), 266.5 ± 234; saturated fat (g), 25.8 ± 16.8; omega-3 fatty acids (g), 1.6 ± 0.99; trans-fatty acids (g), 2.7 ± 1.7; sodium (mg), 2868.5 ± 1388.1; caffeine (mg), 199.9 ± 160.8; alcohol (g), 1.6 ± 0.5; vitamin D (IU), 244 ± 208; and calcium (mg), 1111.7 ± 672.1. The mean (±SD) score as calculated by the Eating Behavior Inventory was 74.9 ± 9.1.

CONCLUSIONS

Obesity, deficient nutrient intake, and poor eating behavior were highly prevalent in our sample of patients with chronic pain who underwent long-term opioid therapy. Larger prospective studies are necessary to assess the eating behavior of patients with chronic pain who are treated with or without opioid analgesics.

摘要

目的

评估一组被诊断为慢性疼痛并接受长期阿片类镇痛治疗的患者的饮食行为和营养摄入情况。

设计

一项采用便利抽样的描述性探索性研究。

地点

一家门诊疼痛康复中心。

参与者

被诊断为慢性疼痛并接受长期阿片类镇痛治疗的患者(N = 50)。

主要观察指标

体重指数、由弗雷德·哈钦森癌症研究中心营养评估共享资源开发的食物频率问卷,以及饮食行为量表。

结果

50名参与者中,分别有14名(28%)和22名(44%)被发现超重和肥胖。男性每日平均(±标准差)热量摄入(千卡)为2008.5±926.0,女性为1694.8±672.4。用求和法计算,水果和蔬菜的每日平均(±标准差)摄入量分别为1.8±1.1份和1.9±1.5份。我们的患者样本显示以下物质的每日平均(±标准差)摄入量如下:添加糖(克),74.4±43.0;纤维(克),17.3±7.5;胆固醇(毫克),266.5±234;饱和脂肪(克),25.8±16.8;ω-3脂肪酸(克),1.6±0.99;反式脂肪酸(克),2.7±1.7;钠(毫克),2868.5±1388.1;咖啡因(毫克),199.9±160.8;酒精(克),1.6±0.5;维生素D(国际单位),244±208;钙(毫克),1111.7±672.1。饮食行为量表计算得出的平均(±标准差)得分为74.9±9.1。

结论

在我们接受长期阿片类治疗的慢性疼痛患者样本中肥胖、营养摄入不足和不良饮食行为非常普遍。有必要开展更大规模的前瞻性研究来评估接受或未接受阿片类镇痛药治疗的慢性疼痛患者的饮食行为。

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