Supramolecular Chemistry Group, Department of Organic Chemistry, Ghent University, Krijgslaan 281-S4, 9000, Ghent, Belgium,
J Mater Sci Mater Med. 2014 May;25(5):1211-25. doi: 10.1007/s10856-013-5034-y. Epub 2013 Aug 23.
The conjunction of polymers and medicine enables the development of new materials that display novel features, opening new ways to administrate drugs, design implants and biosensors, to deliver pharmaceuticals impacting cancer treatment, regenerative medicine or gene therapy. Poly(2-oxazoline)s (POx) constitute a polymer class with exceptional properties for their use in a plethora of different biomedical applications and are proposed as a versatile platform for the development of new medicine. Herein, a global vision of POx as a platform for novel biomaterials is offered, by highlighting the recent advances and breakthroughs in this fascinating field.
聚合物和医学的结合使新型材料的开发成为可能，这些材料具有新颖的特性，为药物管理、植入物和生物传感器设计开辟了新途径，为影响癌症治疗、再生医学或基因治疗的药物输送提供了新方法。聚（2-恶唑啉）（POx）是一类具有特殊性质的聚合物，可用于多种不同的生物医学应用，被提议作为开发新药的通用平台。本文通过强调该迷人领域的最新进展和突破，提供了 POx 作为新型生物材料平台的全面视角。
