Department of Neuropsychiatry, Hirosaki University Graduate School of Medicine, Hirosaki, Japan ; Department of Psychiatry, Kuroishi-Akebono Hospital, Kuroishi, Japan.
Neuropsychiatr Dis Treat. 2013;9:1203-8. doi: 10.2147/NDT.S43280. Epub 2013 Aug 14.
The Brief Assessment of Cognition in Schizophrenia (BACS) is an evaluation of cognitive function that can be completed with more cases. However, there are few studies that compare which factor, disease or aging, is a better determinant of performance on the BACS. The present study aimed to investigate the influences of disease and aging on BACS performance in schizophrenic patients using subjects with a wide range of ages.
Schizophrenic patients (n = 165) and a comparison group (n = 171) were recruited as subjects. All participants completed the Japanese language version of the BACS (BACS-J), and the influences of disease and aging on performance in the BACS were examined with the use of multiple regression analysis.
There was a significant influence of diagnosis and level of education on all six tasks of the BACS and the performance and composite scores. In addition, age was found to influence five tasks and the composite score, the duration of illness influenced four tasks and the composite score, and gender influenced one task and the composite score.
The present study suggests that performance on the BACS was impaired not only by disease but also by level of education and aging.
Brief Assessment of Cognition in Schizophrenia（BACS）是一种认知功能评估，可以在更多病例中完成。然而，很少有研究比较哪种因素（疾病或衰老）对 BACS 表现的影响更大。本研究旨在使用年龄范围较广的受试者来研究疾病和衰老对精神分裂症患者 BACS 表现的影响。
招募了 165 名精神分裂症患者和 171 名对照组作为研究对象。所有参与者都完成了 BACS-J（BACS 的日语版），并使用多元回归分析检查了疾病和衰老对 BACS 表现的影响。
诊断和教育水平对 BACS 的所有六项任务和综合评分均有显著影响。此外，年龄对五项任务和综合评分有影响，病程对四项任务和综合评分有影响，性别对一项任务和综合评分有影响。
本研究表明，BACS 的表现不仅受到疾病的影响，还受到教育水平和衰老的影响。
