Department of Clinical Medicine and Surgery, Physiology Nutrition Unit, University Federico II of Naples, Via Sergio Pansini 5, 80131 Naples, Italy.
Biomed Res Int. 2013;2013:363728. doi: 10.1155/2013/363728. Epub 2013 Jul 30.
We evaluated dietary intake and nutritional-inflammation status in ninety-six renal transplant recipients, 7.2 ± 5.0 years after transplantation. Patients were classified as normoweight (NW), overweight (OW), and obese (OB), if their body mass index was between 18.5 and 24.9, 25.0 and 29.9, and ≥ 30 kg/m(2), respectively. Food composition tables were used to estimate nutrient intakes. The values obtained were compared with those recommended in current nutritional guidelines. 52% of the patients were NW, 29% were OW, and 19% were OB. Total energy, fat, and dietary n-6 PUFAs intake was higher in OB than in NW. IL-6 and hs-CRP were higher in OB than in NW. The prevalence of multidrug regimen was higher in OB. In all patients, total energy, protein, saturated fatty acids, and sodium intake were higher than guideline recommendations. On the contrary, the intake of unsaturated and n-6 and n-3 polyunsaturated fatty acids and fiber was lower than recommended. In conclusion, the prevalence of obesity was high in our patients, and it was associated with inflammation and the assumption of multiple cardiovascular and antidiabetic drugs. Dietary intake did not meet nutritional recommendations in all patients, especially in obese ones, highlighting the need of a long-term nutritional support in renal transplant recipients.
我们评估了 96 例肾移植受者的饮食摄入和营养-炎症状态，这些受者在移植后 7.2±5.0 年。如果患者的体重指数（BMI）在 18.5 到 24.9、25.0 到 29.9 和≥30kg/m² 之间，则将其分类为正常体重（NW）、超重（OW）和肥胖（OB）。使用食物成分表来估计营养素摄入量。将获得的值与当前营养指南中推荐的值进行比较。52%的患者为 NW，29%的患者为 OW，19%的患者为 OB。OB 组的总能量、脂肪和膳食 n-6PUFAs 摄入量高于 NW 组。OB 组的 IL-6 和 hs-CRP 高于 NW 组。OB 组多药物治疗方案的发生率高于 NW 组。在所有患者中，总能量、蛋白质、饱和脂肪酸和钠的摄入量均高于指南推荐值。相反，不饱和脂肪酸、n-6 和 n-3 多不饱和脂肪酸以及纤维的摄入量低于推荐值。总之，我们的患者肥胖患病率较高，且与炎症和使用多种心血管和抗糖尿病药物相关。所有患者的饮食摄入均不符合营养建议，尤其是肥胖患者，这突出了需要对肾移植受者进行长期营养支持。
