Centro de Estudios Fotosintéticos y Bioquímicos (CEFOBI-CONICET), Universidad Nacional de Rosario, Rosario, Argentina.
Biomed Res Int. 2013;2013:792527. doi: 10.1155/2013/792527. Epub 2013 Aug 6.
In the recent years, there has been an increase in the number of metabolomic approaches used, in parallel with proteomic and functional genomic studies. The wide variety of chemical types of metabolites available has also accelerated the use of different techniques in the investigation of the metabolome. At present, metabolomics is applied to investigate several human diseases, to improve their diagnosis and prevention, and to design better therapeutic strategies. In addition, metabolomic studies are also being carried out in areas such as toxicology and pharmacology, crop breeding, and plant biotechnology. In this review, we emphasize the use and application of metabolomics in human diseases and plant research to improve human health.
近年来,代谢组学方法的应用数量不断增加,与蛋白质组学和功能基因组学研究并行。可用代谢物的化学类型多种多样,这也加速了不同技术在代谢组学研究中的应用。目前,代谢组学被应用于研究多种人类疾病,以改善其诊断和预防,并设计更好的治疗策略。此外,代谢组学研究还在毒理学和药理学、作物育种和植物生物技术等领域开展。在本文综述中,我们强调了代谢组学在人类疾病和植物研究中的应用,以改善人类健康。