Departments of Psychology and Electrical Engineering and Princeton Neuroscience Institute, Princeton University, Princeton, NJ 08540.
Proc Natl Acad Sci U S A. 2013 Sep 24;110(39):15806-11. doi: 10.1073/pnas.1313903110. Epub 2013 Sep 9.
The dorsal frontoparietal attention network has been subdivided into at least eight areas in humans. However, the circuitry linking these areas and the functions of different circuit paths remain unclear. Using a combination of neuroimaging techniques to map spatial representations in frontoparietal areas, their functional interactions, and structural connections, we demonstrate different pathways across human dorsal frontoparietal cortex for the control of spatial attention. Our results are consistent with these pathways computing object-centered and/or viewer-centered representations of attentional priorities depending on task requirements. Our findings provide an organizing principle for the frontoparietal attention network, where distinct pathways between frontal and parietal regions contribute to multiple spatial representations, enabling flexible selection of behaviorally relevant information.
人类的背侧额顶注意网络已被细分为至少八个区域。然而，连接这些区域的电路以及不同电路路径的功能仍不清楚。我们使用神经影像学技术组合来绘制额顶区域的空间表示、它们的功能相互作用和结构连接，以证明人类背侧额顶皮质中用于控制空间注意的不同途径。我们的结果与这些途径根据任务要求计算以对象为中心和/或以观察者为中心的注意力优先级表示一致。我们的发现为额顶注意网络提供了一个组织原则，其中额叶和顶叶区域之间的不同途径有助于多种空间表示，从而能够灵活选择与行为相关的信息。
