Department of Microbiology, Federal University of Technology , P.M.B 704, Akure , Nigeria.
Braz J Microbiol. 2009 Apr;40(2):380-6. doi: 10.1590/S1517-838220090002000031. Epub 2009 Jun 1.
Antioxidant and antimicrobial potentials of extracts obtained from four wild mushrooms, Termitomyces clypeatus (TCE), Termitomyces robustus (TRE), Lentinus subnudus (LSE) and Lenzites species (LZE) collected in Nigeria were investigated. LSE and LZE displayed good scavenging activity against 2, 2-Diphenyl-1-Picrylhydrazyl (DPPH) and ferrous ion radicals at concentration of 2 mg/mL. However, TRE and TCE exhibited better superoxide anion scavenging effect at 2 mg/mL. All extracts (TCE, TRE, LSE and LZE) had comparable scavenging effect on hydroxyl radicals as butylated Hydroxytoluene (BHT) used as control. Moreover, extracts from the wild mushrooms were able to inhibit the growth of all indicator organisms at concentrations between 12.5 mg/mL to 100 mg/mL. LSE and LZE, however, showed better antimicrobial effect on the indicator organisms. The results suggest that extracts obtained from the four wild mushrooms may serve as sources of new bioactive compounds with effective antioxidant and antimicrobial activity.
研究了在尼日利亚采集的四种野生蘑菇，即非洲秃马勃（Termitomyces clypeatus，TCE）、粗皮侧耳（Termitomyces robustus，TRE）、皱盖假芝（Lentinus subnudus，LSE）和栓菌属（Lenzites species，LZE）的提取物的抗氧化和抗菌潜力。LSE 和 LZE 在 2 mg/mL 浓度下对 2,2-二苯基-1-苦基肼基（DPPH）和亚铁离子自由基具有良好的清除活性。然而，TRE 和 TCE 在 2 mg/mL 浓度下表现出更好的超氧阴离子清除效果。所有提取物（TCE、TRE、LSE 和 LZE）对羟基自由基的清除效果与用作对照的丁基化羟基甲苯（BHT）相当。此外，这些野生蘑菇的提取物能够在 12.5 mg/mL 至 100 mg/mL 的浓度范围内抑制所有指示生物的生长。然而，LSE 和 LZE 对指示生物表现出更好的抗菌效果。研究结果表明，从这四种野生蘑菇中获得的提取物可能是具有有效抗氧化和抗菌活性的新型生物活性化合物的来源。
