肺炎患者痰液中肺炎链球菌的存活情况。
Survival of Streptococcus pneumoniae in sputum from patients with pneumonia.
作者信息
Williams S G, Kauffman C A
出版信息
J Clin Microbiol. 1978 Jan;7(1):3-5. doi: 10.1128/jcm.7.1.3-5.1978.
The isolation rate of Streptococcus pneumoniae in sputum cultures from patients with pneumococcal pneumonia is low. An investigation was made to determine whether this low yield might be due to loss of pneumocci and/or overgrowth by pharyngeal flora before the specimen is plated. Pneumococcal survival times and pharyngeal overgrowth at 4 degrees C and at room temperature were determined in sputum obtained from 42 patients with pneumococcal pneumonia. It was found that pneumococci survived for long periods in sputum--2.2 +/- 1.4 days at room temperature and 9.5 +/- 3.6 days at 4 degrees C. Overgrowth by pharyngeal flora occurred in only 6 of 42 specimens kept at 4 degrees C and 31 of 42 specimens kept at room temperature. The low yield of S. pneumoniae in sputum from patients with pneumococcal pneumonia is not explained by decreased viability of the organism.
肺炎球菌肺炎患者痰液培养中肺炎链球菌的分离率较低。开展了一项调查，以确定这种低分离率是否可能是由于在标本接种前肺炎球菌丢失和/或咽部菌群过度生长所致。测定了从42例肺炎球菌肺炎患者获得的痰液中肺炎球菌在4℃和室温下的存活时间以及咽部菌群的过度生长情况。结果发现，肺炎球菌在痰液中能长时间存活——在室温下为2.2±1.4天，在4℃下为9.5±3.6天。在42份保存在4℃的标本中，只有6份出现咽部菌群过度生长，而在42份保存在室温的标本中，有31份出现这种情况。肺炎球菌肺炎患者痰液中肺炎链球菌分离率低并非由该菌活力下降所致。
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