Carpentier P H, Maricq H R
Laboratoire d'Hémodynamique Périphérique et de Microcirculation, Hôpital Universitaire, Grenoble, France.
Rheum Dis Clin North Am. 1990 Feb;16(1):75-91.
The considerable amount of consistent data obtained with different techniques regarding the nailfold capillary morphology and function in SSc sheds increasing light on the natural history and the different evolutive patterns of SSc microangiopathy. These data also provide a strong support for a nosologic spectrum of entities like SSc, CREST syndrome, UCTD and prescleroderma RP. From a practical point of view, a more accurate semiologic analysis of RP should provide interesting clues for the clinical management of patients consulting for that vasomotor disturbance. In the next few years, one can predict that quantitation of the microangiopathy, using morphometry and dynamic videomicroscopy, will increase the usefulness of capillary microscopy in clinical practice for the diagnosis and follow-up of such patients.
通过不同技术获得的关于系统性硬化症（SSc）甲襞毛细血管形态和功能的大量一致数据，越来越多地揭示了SSc微血管病变的自然史和不同的演变模式。这些数据也为诸如SSc、CREST综合征、未分化结缔组织病（UCTD）和硬皮病前期雷诺现象（RP）等疾病谱提供了有力支持。从实际角度来看，对RP进行更准确的症状分析应为因该血管舒缩障碍前来咨询的患者的临床管理提供有趣的线索。在未来几年，可以预测，使用形态计量学和动态视频显微镜对微血管病变进行定量分析，将提高毛细血管显微镜检查在这类患者临床实践中的诊断和随访效用。
