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一项评估用于预防和治疗巴基斯坦农村地区儿童腹泻的打包干预措施(“腹泻包”)的可接受性、可行性和影响的研究。

A study to evaluate the acceptability, feasibility and impact of packaged interventions ("Diarrhea Pack") for prevention and treatment of childhood diarrhea in rural Pakistan.

作者信息

Habib Muhammad Atif, Soofi Sajid, Sadiq Kamran, Samejo Tariq, Hussain Musawar, Mirani Mushtaq, Rehmatullah Asmatullah, Ahmed Imran, Bhutta Zulfiqar A

机构信息

Department of Paediatrics and Child Health, Women and Child Health Division, Aga Khan University, Karachi, Pakistan.

出版信息

BMC Public Health. 2013 Oct 3;13:922. doi: 10.1186/1471-2458-13-922.

Abstract

BACKGROUND

Diarrhea remains one of the leading public health issues in developing countries and is a major contributor in morbidity and mortality in children under five years of age. Interventions such as ORS, Zinc, water purification and improved hygiene and sanitation can significantly reduce the diarrhea burden but their coverage remains low and has not been tested as packaged intervention before. This study attempts to evaluate the package of evidence based interventions in a "Diarrhea Pack" through first level health care providers at domiciliary level in community based settings. This study sought to evaluate the acceptability, feasibility and impact of diarrhea Pack on diarrhea burden.

METHODS

A cluster randomized design was used to evaluate the objectives of the project a union council was considered as a cluster for analysis, a total of eight clusters, four in intervention and four in control were included in the study. We conducted a baseline survey in all clusters followed by the delivery of diarrhea Pack in intervention clusters through community health workers at domiciliary level and through sales promoters to health care providers and pharmacies. Four quarterly surveillance rounds were conducted to evaluate the impact of diarrhea pack in all clusters by an independent team of Field workers.

RESULTS

Both the intervention and control clusters were similar at the baseline but as the study progress we found a significant increase in uptake of ORS and Zinc along with the reduction in antibiotic use, diarrhea burden and hospitalization in intervention clusters when compared with the control clusters. We found that the Diarrhea Pack was well accepted with all of its components in the community.

CONCLUSION

The intervention was well accepted and had a productive impact on the uptake of ORS and zinc and reduction in the use of antibiotics. It is feasible to deliver interventions such as diarrhea pack through community health workers in community settings. The intervention has the potential to be scaled up at national level.

摘要

背景

腹泻仍然是发展中国家主要的公共卫生问题之一,也是五岁以下儿童发病和死亡的主要原因。口服补液盐、锌、水净化以及改善卫生和环境卫生等干预措施可显著减轻腹泻负担,但其覆盖率仍然较低,且此前尚未作为综合干预措施进行测试。本研究试图通过社区基层的一级医疗服务提供者,评估“腹泻包”中基于证据的综合干预措施。本研究旨在评估腹泻包对腹泻负担的可接受性、可行性和影响。

方法

采用整群随机设计来评估项目目标,将一个联合委员会视为一个分析群组,该研究共纳入八个群组,四个为干预组,四个为对照组。我们在所有群组中进行了基线调查,随后通过社区卫生工作者在家庭层面以及通过促销员向医疗服务提供者和药店发放腹泻包。由一组独立的现场工作人员进行四轮季度监测,以评估腹泻包对所有群组的影响。

结果

干预组和对照组在基线时相似,但随着研究进展,我们发现与对照组相比,干预组口服补液盐和锌的使用显著增加,同时抗生素使用、腹泻负担和住院率有所降低。我们发现腹泻包在社区中其所有成分都得到了很好的接受。

结论

该干预措施得到了很好的接受,对口服补液盐和锌的使用以及抗生素使用的减少产生了积极影响。通过社区卫生工作者在社区环境中提供腹泻包等干预措施是可行的。该干预措施有在国家层面扩大规模的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0604/3851134/badfcf21099e/1471-2458-13-922-1.jpg

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