用于多模态诊断成像和光热癌症治疗的钆共轭金纳米壳
Gadolinium-conjugated gold nanoshells for multimodal diagnostic imaging and photothermal cancer therapy.
作者信息
Coughlin Andrew J, Ananta Jeyarama S, Deng Nanfu, Larina Irina V, Decuzzi Paolo, West Jennifer L
机构信息
Department of Bioengineering, Rice University, 6100 Main Street, MS-142, Houston, TX, 77005, USA.
出版信息
Small. 2014 Feb 12;10(3):556-65. doi: 10.1002/smll.201302217. Epub 2013 Sep 23.
Abstract
Multimodal imaging offers the potential to improve diagnosis and enhance the specificity of photothermal cancer therapy. Toward this goal, gadolinium-conjugated gold nanoshells are engineered and it is demonstrated that they enhance contrast for magnetic resonance imaging, X-ray, optical coherence tomography, reflectance confocal microscopy, and two-photon luminescence. Additionally, these particles effectively convert near-infrared light to heat, which can be used to ablate cancer cells. Ultimately, these studies demonstrate the potential of gadolinium-nanoshells for image-guided photothermal ablation.
摘要
多模态成像具有改善诊断并提高光热癌症治疗特异性的潜力。为实现这一目标，人们设计了钆共轭金纳米壳，并证明它们能增强磁共振成像、X射线、光学相干断层扫描、反射共聚焦显微镜和双光子发光的对比度。此外，这些粒子能有效地将近红外光转化为热量，可用于消融癌细胞。最终，这些研究证明了钆纳米壳在图像引导光热消融方面的潜力。
相似文献
1
Gadolinium-conjugated gold nanoshells for multimodal diagnostic imaging and photothermal cancer therapy.用于多模态诊断成像和光热癌症治疗的钆共轭金纳米壳
Small. 2014 Feb 12;10(3):556-65. doi: 10.1002/smll.201302217. Epub 2013 Sep 23.
2
BSA-Bioinspired Gadolinium Hybrid-Functionalized Hollow Gold Nanoshells for NIRF/PA/CT/MR Quadmodal Diagnostic Imaging-Guided Photothermal/Photodynamic Cancer Therapy.BSA-仿生钆杂化功能化空心金纳米壳用于 NIRF/PA/CT/MR 四模态诊断成像引导光热/光动力癌症治疗。
ACS Appl Mater Interfaces. 2017 Nov 22;9(46):40017-40030. doi: 10.1021/acsami.7b11926. Epub 2017 Nov 8.
3
Gold nanoshelled liquid perfluorocarbon nanocapsules for combined dual modal ultrasound/CT imaging and photothermal therapy of cancer.金纳米壳液态全氟碳纳米胶囊用于癌症的联合超声/CT 双模态成像和光热治疗。
Small. 2014 Mar 26;10(6):1220-7. doi: 10.1002/smll.201302252. Epub 2014 Feb 5.
4
Rational Design of Branched Nanoporous Gold Nanoshells with Enhanced Physico-Optical Properties for Optical Imaging and Cancer Therapy.具有增强的物理光学特性的支化纳米多孔金纳米壳的合理设计用于光学成像和癌症治疗。
ACS Nano. 2017 Jun 27;11(6):6102-6113. doi: 10.1021/acsnano.7b02048. Epub 2017 Jun 15.
5
GdO-mesoporous silica/gold nanoshells: A potential dual / contrast agent for MRI-guided localized near-IR photothermal therapy.钆介孔硅/金纳米壳：一种潜在的磁共振成像引导局部近红外光热治疗的双/对比剂。
Proc Natl Acad Sci U S A. 2022 Jul 19;119(29):e2123527119. doi: 10.1073/pnas.2123527119. Epub 2022 Jul 11.
6
Kinetically and thermodynamically controlled one-pot growth of gold nanoshells with NIR-II absorption for multimodal imaging-guided photothermal therapy.动力学和热力学控制的一锅法生长具有近红外二区吸收的金纳米壳，用于多模态成像引导光热治疗。
J Nanobiotechnology. 2023 Apr 28;21(1):138. doi: 10.1186/s12951-023-01907-1.
7
Macrophage Cell Membrane Camouflaged Au Nanoshells for in Vivo Prolonged Circulation Life and Enhanced Cancer Photothermal Therapy.巨噬细胞膜伪装的金纳米壳用于体内延长循环寿命和增强癌症光热治疗
ACS Appl Mater Interfaces. 2016 Apr 20;8(15):9610-8. doi: 10.1021/acsami.6b00853. Epub 2016 Apr 8.
8
Target-specific near-IR induced drug release and photothermal therapy with accumulated Au/Ag hollow nanoshells on pulmonary cancer cell membranes.基于肺癌细胞膜上 Au/Ag 中空纳米壳的靶向近红外光诱导药物释放和光热治疗。
Biomaterials. 2015 Mar;45:81-92. doi: 10.1016/j.biomaterials.2014.12.036. Epub 2015 Jan 16.
9
Controlled synthesis of multilayered gold nanoshells for enhanced photothermal therapy and SERS detection.用于增强光热治疗和 SERS 检测的多层金纳米壳的可控合成。
Small. 2015 Jan 7;11(1):77-83. doi: 10.1002/smll.201402149. Epub 2014 Sep 15.
10
Gold Nanoshells: Combined Near Infrared Photothermal Therapy and Chemotherapy Using Gold Nanoshells Coated Liposomes to Enhance Antitumor Effect (Small 30/2016).金纳米壳：利用金纳米壳包覆脂质体进行近红外光热化疗以增强抗肿瘤效果（Small 30/2016）。
Small. 2016 Aug;12(30):4102. doi: 10.1002/smll.201670150.
引用本文的文献
1
E-Selectin Targeted Gold Nanoshells to Inhibit Breast Cancer Cell Binding to Lung Endothelial Cells.靶向E-选择素的金纳米壳抑制乳腺癌细胞与肺内皮细胞的结合。
ACS Appl Nano Mater. 2023 Jan 27;6(2):1315-1324. doi: 10.1021/acsanm.2c04967. Epub 2023 Jan 9.
2
Application of Nanoparticles in the Diagnosis of Gastrointestinal Diseases: A Complete Future Perspective.纳米颗粒在胃肠道疾病诊断中的应用：全面的未来展望。
Int J Nanomedicine. 2023 Jul 26;18:4143-4170. doi: 10.2147/IJN.S413141. eCollection 2023.
3
Optical Microscopy Systems for the Detection of Unlabeled Nanoparticles.用于检测未标记纳米粒子的光学显微镜系统。
Int J Nanomedicine. 2022 May 13;17:2139-2163. doi: 10.2147/IJN.S355007. eCollection 2022.
4
Hollow micro and nanostructures for therapeutic and imaging applications.用于治疗和成像应用的中空微纳结构。
J Drug Deliv Sci Technol. 2020 Dec;60. doi: 10.1016/j.jddst.2020.102094. Epub 2020 Sep 14.
5
Plasmonic Nanoparticles: Basics to Applications (I).等离子体纳米粒子：基础到应用（一）。
Adv Exp Med Biol. 2021;1309:133-159. doi: 10.1007/978-981-33-6158-4_6.
6
Smart Gold Nanostructures for Light Mediated Cancer Theranostics: Combining Optical Diagnostics with Photothermal Therapy.用于光介导癌症诊疗的智能金纳米结构：将光学诊断与光热疗法相结合
Adv Sci (Weinh). 2020 Jun 18;7(15):1903441. doi: 10.1002/advs.201903441. eCollection 2020 Aug.
7
Production of gold/silver doped carbon nanocomposites for effective photothermal therapy of colon cancer.制备金/银掺杂碳纳米复合材料用于结肠癌的有效光热治疗。
Sci Rep. 2020 May 6;10(1):7618. doi: 10.1038/s41598-020-64225-8.
8
Vascular Interventional Radiology-Guided Photothermal Therapy of Colorectal Cancer Liver Metastasis with Theranostic Gold Nanorods.血管介入放射学引导的治疗诊断一体化金纳米棒用于结直肠癌肝转移的光热治疗。
ACS Nano. 2018 Jul 24;12(7):6597-6611. doi: 10.1021/acsnano.8b01424. Epub 2018 Jul 6.
9
Temperature-controlled, phase-transition ultrasound imaging-guided photothermal-chemotherapy triggered by NIR light.温度控制、相转变超声成像引导的光热-化学治疗，由近红外光触发。
Theranostics. 2018 Apr 30;8(11):3059-3073. doi: 10.7150/thno.23885. eCollection 2018.
10
Big Potential from Small Agents: Nanoparticles for Imaging-Based Companion Diagnostics.从小分子到大潜能：基于成像的伴随诊断用纳米颗粒。
ACS Nano. 2018 Mar 27;12(3):2106-2121. doi: 10.1021/acsnano.7b07252. Epub 2018 Mar 1.
本文引用的文献
1
Evaluation of the toxicity of intravenous delivery of auroshell particles (gold-silica nanoshells).金壳粒子（金-硅纳米壳）静脉注射的毒性评估。
Int J Toxicol. 2012 Nov-Dec;31(6):584-94. doi: 10.1177/1091581812465969. Epub 2012 Dec 4.
2
Effects of photoacoustic imaging and photothermal ablation therapy mediated by targeted hollow gold nanospheres in an orthotopic mouse xenograft model of glioma.靶向中空金纳米球介导的光声成像和光热消融治疗在胶质瘤原位移植模型中的作用。
Cancer Res. 2011 Oct 1;71(19):6116-21. doi: 10.1158/0008-5472.CAN-10-4557. Epub 2011 Aug 19.
3
Intra-organ Biodistribution of Gold Nanoparticles Using Intrinsic Two-photon Induced Photoluminescence.利用本征双光子诱导光致发光研究金纳米颗粒的器官内生物分布
Lasers Surg Med. 2010 Sep;42(7):630-639. doi: 10.1002/lsm.20935.
4
Time-lapse imaging of disease progression in deep brain areas using fluorescence microendoscopy.使用荧光显微内镜对深部脑区疾病进展进行延时成像。
Nat Med. 2011 Feb;17(2):223-8. doi: 10.1038/nm.2292. Epub 2011 Jan 16.
5
Oxidative stress mediates the effects of Raman-active gold nanoparticles in human cells.氧化应激介导了具有拉曼活性的金纳米粒子在人细胞中的作用。
Small. 2011 Jan 3;7(1):126-36. doi: 10.1002/smll.201001466.
6
Geometrical confinement of gadolinium-based contrast agents in nanoporous particles enhances T1 contrast.纳米多孔颗粒中镧系元素（钆）造影剂的几何约束增强了 T1 对比。
Nat Nanotechnol. 2010 Nov;5(11):815-21. doi: 10.1038/nnano.2010.203. Epub 2010 Oct 24.
7
Antibody-conjugated gold-gold sulfide nanoparticles as multifunctional agents for imaging and therapy of breast cancer.抗体偶联的金-金硫化物纳米颗粒作为乳腺癌成像和治疗的多功能试剂。
Int J Nanomedicine. 2010 Aug 9;5:445-54. doi: 10.2147/ijn.s10881.
8
Surface modification of PLGA nanospheres with Gd-DTPA and Gd-DOTA for high-relaxivity MRI contrast agents.PLGA 纳米球表面修饰 Gd-DTPA 和 Gd-DOTA 用于高弛豫率 MRI 对比剂。
Biomaterials. 2010 Nov;31(33):8716-23. doi: 10.1016/j.biomaterials.2010.07.095. Epub 2010 Aug 24.
9
Multimodality imaging probes: design and challenges.多模态成像探针：设计与挑战。
Chem Rev. 2010 May 12;110(5):3146-95. doi: 10.1021/cr9003538.
10
Multimodal gadolinium-enriched DNA-gold nanoparticle conjugates for cellular imaging.用于细胞成像的多模态富钆DNA-金纳米颗粒缀合物
Angew Chem Int Ed Engl. 2009;48(48):9143-7. doi: 10.1002/anie.200904666.
Zotero 插件