Valkova B, Laurence D J
J Clin Pathol. 1985 Aug;38(8):886-92. doi: 10.1136/jcp.38.8.886.
A preliminary analysis was undertaken to ascertain whether a Leitz TAS (Texture Analyse System) video camera system, which is computer controlled, could be used to detect abnormal cells in cervical smears. Immunocytochemical together with haemalum nuclear staining was used for the epithelial membrane antigen. It was possible to detect abnormal cells in routinely prepared smears taken from patients with various degrees of cervical neoplasia, including the earliest stages, but metaplastic cells were not detected by the system. Smears from patients assessed as normal by routine cytology gave a low incidence of positive results due to occasional overlapping of cells or the presence of air bubbles. This system seems to offer a new possibility for rapid automated cytometry of cervical smears.
进行了一项初步分析，以确定计算机控制的徕卡TAS（纹理分析系统）视频摄像系统是否可用于检测宫颈涂片异常细胞。上皮膜抗原检测采用免疫细胞化学结合苏木精核染色法。该系统能够在取自不同程度宫颈肿瘤患者（包括最早期）的常规制备涂片中检测到异常细胞，但未检测到化生细胞。因细胞偶尔重叠或存在气泡，经常规细胞学评估为正常的患者涂片阳性结果发生率较低。该系统似乎为宫颈涂片的快速自动细胞计数提供了一种新的可能。
