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迈向宫颈肿瘤定量细胞学筛查的自动化程序

Towards an automated procedure for the quantitative cytological screening of cervical neoplasms.

作者信息

Sincock A M, Middleton J, Moncrieff D

出版信息

J Clin Pathol. 1983 May;36(5):535-8. doi: 10.1136/jcp.36.5.535.

Abstract

Integrating microdensitometry has been used to quantify the glycoprotein, epithelial membrane antigen (EMA), which is frequently expressed on the cytoplasmic membrane of neoplastic cells of the cervix uteri. The technique was able to identify and quantify the antigen over a wide concentration range and could also be semi-automated using a microcomputer interfaced to the microdensitometer and programmed with the simple high level language BASIC.

摘要

积分显微密度测定法已被用于定量糖蛋白,即上皮膜抗原(EMA),该抗原常在子宫颈肿瘤细胞的细胞质膜上表达。这项技术能够在很宽的浓度范围内识别和定量该抗原,并且还可以使用与显微密度计相连的微型计算机并通过简单的高级语言BASIC进行编程来实现半自动化。

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本文引用的文献

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Distribution of epithelial membrane antigen in normal and neoplastic tissues and it value in diagnostic tumor pathology.
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