纳米粒子在肾脏疾病的检测和治疗中的应用。
Applications of nanoparticles in the detection and treatment of kidney diseases.
机构信息
Department of Biomedical Engineering, Lerner Research Institute and Glickman Urologic and Kidney Institute, Cleveland Clinic, Cleveland, OH; and Department of Biomedical Engineering, Lerner Research Institute and Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH.
出版信息
Adv Chronic Kidney Dis. 2013 Nov;20(6):454-65. doi: 10.1053/j.ackd.2013.07.006.
Abstract
Nanoparticles have emerged in the medical field as a technology well suited for the diagnosis and treatment of various disease states. They have been heralded as efficacious in terms of improved therapeutic efficacy and reduction of treatment side effects in some cases. Various nanomaterials have been developed that can be tagged with targeting moieties as well as with drug delivery and imaging capability or a combination of both as a theranostic agent. These nanomaterials have been investigated for treatment and detection of various pathological conditions. The emphasis of this review is to demonstrate current research and clinical applications for nanoparticles in the diagnosis and treatment of kidney diseases.
摘要
纳米颗粒在医学领域已经崭露头角，是一种非常适合诊断和治疗各种疾病状态的技术。在某些情况下，它们在提高治疗效果和减少治疗副作用方面被证明是有效的。已经开发出各种纳米材料，可以将靶向部分以及药物输送和成像能力或两者结合作为治疗诊断剂进行标记。这些纳米材料已被用于治疗和检测各种病理状况。本文的重点是展示纳米颗粒在肾脏疾病的诊断和治疗中的当前研究和临床应用。
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