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中国高致病性禽流感 A(H5N1)病毒 2.3.4 分支的新型变异株。

Novel variants of clade 2.3.4 highly pathogenic avian influenza A(H5N1) viruses, China.

出版信息

Emerg Infect Dis. 2013 Dec;19(12):2021-4. doi: 10.3201/eid1912.130340.

DOI:10.3201/eid1912.130340
PMID:24274396
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3840869/
Abstract

We characterized 7 highly pathogenic avian influenza A(H5N1) viruses isolated from poultry in China during 2009-2012 and found that they belong to clade 2.3.4 but do not fit within the 3 defined subclades. Antigenic drift in subtype H5N1 variants may reduce the efficacy of vaccines designed to control these viruses in poultry.

摘要

我们对 2009-2012 年期间在中国家禽中分离到的 7 株高致病性禽流感 H5N1 病毒进行了特征分析，发现它们属于 2.3.4 分支，但不属于已定义的 3 个亚分支。亚型 H5N1 变异株的抗原漂移可能降低针对这些病毒的疫苗的防控效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8739/3840869/8ff4d8c6538d/13-0340-F.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8739/3840869/8ff4d8c6538d/13-0340-F.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8739/3840869/8ff4d8c6538d/13-0340-F.jpg

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3
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