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分离的猪上皮内淋巴细胞的形态学和功能特征

Morphology and functional characteristics of isolated porcine intraepithelial lymphocytes.

作者信息

Wilson A D, Stokes C R, Bourne F J

出版信息

Immunology. 1986 Sep;59(1):109-13.

PMID:2428733
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1453143/
Abstract

We have examined the morphology and functional characteristics of porcine intraepithelial lymphocytes (IEL). A subpopulation of IEL contains granules as seen in other species, and their ultrastructure was also similar. They were capable of producing T-cell growth factor and interferon on in vitro stimulation. IEL killed P815 cells in the presence of PHA, but did not kill K562 cells.

摘要

我们研究了猪上皮内淋巴细胞（IEL）的形态和功能特性。IEL的一个亚群含有颗粒，这与其他物种所见相似，其超微结构也相似。它们在体外刺激下能够产生T细胞生长因子和干扰素。IEL在PHA存在的情况下可杀死P815细胞，但不能杀死K562细胞。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b870/1453143/03912984c87e/immunology00174-0102-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b870/1453143/764296bbb14e/immunology00174-0102-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b870/1453143/03912984c87e/immunology00174-0102-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b870/1453143/764296bbb14e/immunology00174-0102-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b870/1453143/03912984c87e/immunology00174-0102-b.jpg

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本文引用的文献

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Intraepithelial, lamina propria and Peyer's patch lymphocytes of the rat small intestine: isolation and characterization in terms of immunoglobulin markers and receptors for monoclonal antibodies.大鼠小肠上皮内、固有层和派尔集合淋巴结淋巴细胞：根据免疫球蛋白标记物和单克隆抗体受体进行分离与特性鉴定
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Functional properties of lymphocytes isolated from murine small intestinal epithelium.
维生素 E 和α-硫辛酸对肉鸡木质胸肉肌病相关肠发育的影响。
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Development of mucosal and systemic lymphoproliferative responses and protective immunity to human group A rotaviruses in a gnotobiotic pig model.无菌猪模型中对人A组轮状病毒的黏膜和全身淋巴增殖反应及保护性免疫的发展
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Lymphoid and non-lymphoid cells in the epithelium and lamina propria of intestinal mucosa of pigs.猪肠道黏膜上皮和固有层中的淋巴细胞和非淋巴细胞。
Gut. 1994 Nov;35(11):1582-9. doi: 10.1136/gut.35.11.1582.
10
Experimental studies of immunologically mediated enteropathy. II. Role of natural killer cells in the intestinal phase of murine graft-versus-host reaction.免疫介导性肠病的实验研究。II. 自然杀伤细胞在小鼠移植物抗宿主反应肠道阶段中的作用。
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Investigation of porcine natural-killer cell activity with reference to African swine-fever virus infection.关于非洲猪瘟病毒感染对猪自然杀伤细胞活性的研究。
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Eur J Immunol. 1984 Nov;14(11):1066-9. doi: 10.1002/eji.1830141121.
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Eur J Immunol. 1984 Jan;14(1):33-9. doi: 10.1002/eji.1830140107.