Department of Biochemistry, State University of Leiden, P.O. Box 9505, 2300 RA, Leiden, The Netherlands.
Plant Mol Biol. 1984 Nov;3(6):379-84. doi: 10.1007/BF00033385.
A comparison was made of the amino acid sequences of the proteins encoded by RNAs 1 and 2 of alfalfa mosaic virus (A1MV) and brome mosaic virus (BMV), and the 126K and 183K proteins encoded by tobacco mosaic virus (TMV). Three blocks of extensive homology of about 200 to 350 amino acids each were observed. Two of these blocks are located in the A1MV and BMV RNA 1 encoded proteins and the TMV encoded 126K protein; they are situated at the N-terminus and C-terminus, respectively. The third block is located in the A1MV and BMV RNA 2 encoded proteins and the C-terminal part of the TMV encoded 183K protein. These homologies are discussed with respect to the functional equivalence of these putative replicase proteins and a possible evolutionary connection between A1MV, BMV and TMV.
对苜蓿花叶病毒（A1MV）和雀麦花叶病毒（BMV）的 RNA1 和 RNA2 编码的蛋白质以及烟草花叶病毒（TMV）编码的 126K 和 183K 蛋白质的氨基酸序列进行了比较。观察到三个大约 200 到 350 个氨基酸的广泛同源块。其中两个块分别位于 A1MV 和 BMV RNA1 编码的蛋白质和 TMV 编码的 126K 蛋白中；它们分别位于 N 端和 C 端。第三个块位于 A1MV 和 BMV RNA2 编码的蛋白质和 TMV 编码的 183K 蛋白的 C 末端。讨论了这些同源性与这些假定的复制酶蛋白的功能等效性以及 A1MV、BMV 和 TMV 之间可能的进化关系。
