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术中心脏骤停的发生率及中期生存率。

Frequency of intraoperative cardiac arrest and medium-term survival.

作者信息

Sebbag Ilana, Carmona Maria José Carvalho, Gonzalez Maria Margarita Castro, Alcântara Hermes Marcel, Lelis Rolison Gustavo Bravo, Toledo Flavia de Oliveira, Aranha Gustavo Fábio, Nuzzi Rafael Ximenes do Prado, Auler José Otávio Costa

机构信息

Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, Instituto Central, São PauloBrazil.

出版信息

Sao Paulo Med J. 2013;131(5):309-14. doi: 10.1590/1516-3180.2013.1315507.

Abstract

CONTEXT AND OBJECTIVE

Although advances in surgical and anesthetic techniques have reduced perioperative morbidity-mortality, the survival rate following cardiac arrest remains low. The aim of this study was to evaluate, over the course of one year, the prevalence of intraoperative cardiac arrest and the 30-day survival rate after this event in a tertiary teaching hospital.

DESIGN AND SETTING

Prospective cohort study in a tertiary teaching hospital.

METHODS

Following approval by the institutional ethics committee, anesthetic procedures and cases of intraoperative cardiac arrest between January and December 2007 were evaluated. Patients undergoing cardiac surgery were excluded. The data were gathered prospectively using the modified Utstein model, with evaluation of demographic data, pre-arrest conditions, intraoperative care, care during arrest and postoperative outcome up to the 30th day. The data were recorded by the attending anesthesiologist.

RESULTS

During the study period, 40,379 anesthetic procedures were performed, and 52 cases of intraoperative cardiac arrest occurred (frequency of 13:10,000). Among these, 69% presented spontaneous return of circulation after the initial arrest, and only 25% survived for 30 days after the event. The following factors were associated with shorter survival: American Society of Anesthesiologists physical status IV and V, emergency surgery, hemorrhagic events, hypovolemia as the cause of arrest and use of atropine during resuscitation.

CONCLUSIONS

Although the frequency of cardiac arrest in the surgical environment has declined and resources to attend to this exist, the survival rate is low. Factors associated with worst prognosis are more frequent in critical patients.

摘要

背景与目的

尽管外科手术和麻醉技术的进步降低了围手术期的发病率和死亡率,但心脏骤停后的生存率仍然很低。本研究的目的是在一家三级教学医院中,评估一年内术中心脏骤停的发生率以及该事件后的30天生存率。

设计与背景

在一家三级教学医院进行的前瞻性队列研究。

方法

经机构伦理委员会批准后,对2007年1月至12月期间的麻醉程序和术中心脏骤停病例进行评估。接受心脏手术的患者被排除在外。使用改良的Utstein模型前瞻性收集数据,评估人口统计学数据、心脏骤停前状况、术中护理、心脏骤停期间的护理以及直至第30天的术后结局。数据由主治麻醉医生记录。

结果

在研究期间,共进行了40379例麻醉程序,发生了52例术中心脏骤停(发生率为13:10000)。其中,69%在初次心脏骤停后出现自主循环恢复,而事件发生后只有25%存活30天。以下因素与较短的生存期相关:美国麻醉医师协会身体状况IV级和V级、急诊手术、出血事件、作为心脏骤停原因的低血容量以及复苏期间使用阿托品。

结论

尽管手术环境中心脏骤停的发生率有所下降且有相应的应对资源,但生存率仍然很低。与最差预后相关的因素在危重症患者中更为常见。

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