Chest Research Foundation, Marigold Complex, Kalyaninagar, Pune 411014, India.
Expert Rev Respir Med. 2014 Feb;8(1):89-99. doi: 10.1586/17476348.2014.854168. Epub 2013 Dec 10.
The pressurized metered dose inhalers and dry powder inhalers are the most widely used devices for inhalation therapy in asthma and chronic obstructive pulmonary disease; each of these devices have certain advantages and disadvantages that impact their use. Motivation from the virtues of these devices led to the development of breath-actuated or breath-activated metered dose inhalers. A history of the breath-actuated inhalers, the development and technical aspects, studies about the usability, inhalation technique and patient preference, lung deposition and impact on lung function are presented in this review article. This review presents the use of breath-actuated inhalers in asthma and chronic obstructive pulmonary disease and in children and elderly; and a brief economic evaluation aims to put the clinical efficacy and ease-of-use of the breath-actuated inhaler into perspective by understanding the long-term cost benefits associated with this device.
压力定量吸入器和干粉吸入器是哮喘和慢性阻塞性肺疾病中最广泛使用的吸入治疗装置；这些装置各有优缺点，影响其使用。这些装置的优点激发了呼吸驱动或呼吸触发定量吸入器的发展。本文综述了呼吸驱动吸入器的历史、发展和技术方面、关于可用性、吸入技术和患者偏好、肺部沉积和对肺功能的影响的研究。本文综述了呼吸驱动吸入器在哮喘和慢性阻塞性肺疾病以及儿童和老年人中的应用；并进行了简要的经济评估，旨在通过了解与该装置相关的长期成本效益，从临床疗效和易用性的角度来评估呼吸驱动吸入器。
