State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Zhang Jiang Hi-Tech Park, Shanghai 201203, P. R. China, (phone: +86-21-50805813); Present address: School of Chemistry and Chemical Engineering, Central South University, Changsha 410083, P. R. China.
Chem Biodivers. 2013 Dec;10(12):2161-96. doi: 10.1002/cbdv.201200122.
This review covers structural diversity and biological activities of terpenes from soft corals of the genus of Sarcophyton, reported from 1995 to July, 2011. During this period, besides undefined species, 16 species of the genus Sarcophyton, from different geographical areas, had been chemically examined. Two hundred and five terpenes had been isolated from this genus, including eleven sesquiterpenes, 165 diterpenes, 29 biscembranoids, some of which had novel skeletons. They exhibited various biological features, such as antifeedant, anti-inflammatory, antiviral, and antifouling activities.
本综述涵盖了自 1995 年至 2011 年 7 月期间，从软珊瑚属 Sarcophyton 中分离得到的萜类化合物的结构多样性和生物活性。在此期间，除了未定义的物种外，还对来自不同地理区域的 16 种 Sarcophyton 属的物种进行了化学研究。从该属中分离出了 205 种萜类化合物，包括 11 种倍半萜、165 种二萜、29 种双环二萜，其中一些具有新颖的骨架。它们表现出各种生物特性，如抗营养、抗炎、抗病毒和防污活性。
