Dama Madhukar Shivajirao, Bhat M Narayana
Institute of Wildlife Veterinary Research, Kodagu District, Karnataka, India.
F1000Res. 2013 Feb 12;2:40. doi: 10.12688/f1000research.2-40.v1. eCollection 2013.
As mobile phone usage is growing rapidly, there is a need for a comprehensive analysis of the literature to inform scientific debates about the adverse effects of mobile phone radiation on sperm quality traits. Therefore, we conducted a meta-analysis of the eligible published research studies on human males of reproductive age. Eleven studies were eligible for this analysis. Based on the meta-analysis, mobile phone use was significantly associated with deterioration in semen quality (Hedges's g = -0.547; 95% CI: -0.713, -0.382; p < 0.001). The traits particularly affected adversely were sperm concentration, sperm morphology, sperm motility, proportion of non-progressive motile sperm (%), proportion of slow progressive motile sperm (%), and sperm viability. Direct exposure of spermatozoa to mobile phone radiation with study designs also significantly deteriorated the sperm quality (Hedges's g = -2.233; 95% CI: -2.758, -1.708; < 0.001), by reducing straight line velocity, fast progressive motility, Hypo-osmotic swelling (HOS) test score, major axis (µm), minor axis (µm), total sperm motility, perimeter (µm), area (µm ), average path velocity, curvilinear velocity, motile spermatozoa, and acrosome reacted spermatozoa (%). The strength of evidence for the different outcomes varied from very low to very high. The analysis shows that mobile phone use is possibly associated with a number of deleterious effects on the spermatozoa.
随着手机使用的迅速增长，有必要对文献进行全面分析，为关于手机辐射对精子质量特征的不良影响的科学辩论提供信息。因此，我们对已发表的关于育龄男性的合格研究进行了荟萃分析。有11项研究符合该分析的条件。基于荟萃分析，手机使用与精液质量下降显著相关（Hedges's g = -0.547；95%置信区间：-0.713，-0.382；p < 0.001）。受到特别不利影响的特征包括精子浓度、精子形态、精子活力、非进行性运动精子比例（%）、缓慢进行性运动精子比例（%）和精子存活率。精子直接暴露于手机辐射下的研究设计也显著降低了精子质量（Hedges's g = -2.233；95%置信区间：-2.758，-1.708；p < 0.001），表现为直线速度、快速进行性运动能力、低渗肿胀（HOS）试验评分、长轴（μm）、短轴（μm）、总精子活力、周长（μm）、面积（μm²）、平均路径速度、曲线速度、运动精子和顶体反应精子比例（%）降低。不同结果的证据强度从非常低到非常高不等。分析表明，使用手机可能会对精子产生多种有害影响。
