两性霉素 B 与特比萘芬联合治疗与着色真菌病相关的黑曲霉
Combination of Amphotericin B and Terbinafine against Melanized Fungi Associated with Chromoblastomycosis.
机构信息
Department of Medical Microbiology, People's Hospital of Suzhou National New & Hi-Tech Industrial Development Zone, Jiangsu, China.
Shanghai Institute of Medical Mycology, Department of Dermatology, Changzheng Hospital, Second Military Medical University, Shanghai, China.
出版信息
Antimicrob Agents Chemother. 2018 May 25;62(6). doi: 10.1128/AAC.00270-18. Print 2018 Jun.
Abstract
Our studies showed that a combination of amphotericin B and terbinafine had synergistic effects against the majority of melanized fungi associated with chromoblastomycosis (CBM) and similar infections, including those with , , , , , , , and This drug combination could provide an option for the treatment of severe or unresponsive cases of CBM, particularly in cases due to species of and .
摘要
我们的研究表明，两性霉素 B 和特比萘芬联合使用对大多数与着色芽生菌病（CBM）和类似感染相关的黑曲霉具有协同作用，包括 、 、 、 、 、 、 。这种药物联合治疗可能为治疗严重或对 CBM 反应不佳的病例提供一种选择，特别是由 和 引起的病例。
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