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本文引用的文献

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Molecular Epidemiology of Agents of Human Chromoblastomycosis in Brazil with the Description of Two Novel Species.巴西人类着色芽生菌病病原体的分子流行病学及两个新物种的描述
PLoS Negl Trop Dis. 2016 Nov 28;10(11):e0005102. doi: 10.1371/journal.pntd.0005102. eCollection 2016 Nov.
2
Chromoblastomycosis.着色芽生菌病
Clin Microbiol Rev. 2017 Jan;30(1):233-276. doi: 10.1128/CMR.00032-16.
3
Systemic Antifungal Agents: Current Status and Projected Future Developments.全身性抗真菌药物：现状与未来发展展望
Methods Mol Biol. 2017;1508:107-139. doi: 10.1007/978-1-4939-6515-1_5.
4
Combination of Amphotericin B and Flucytosine against Neurotropic Species of Melanized Fungi Causing Primary Cerebral Phaeohyphomycosis.两性霉素B与氟胞嘧啶联合用于治疗引起原发性脑暗色丝孢霉病的嗜神经黑色素真菌菌种
Antimicrob Agents Chemother. 2016 Mar 25;60(4):2346-51. doi: 10.1128/AAC.02526-15. Print 2016 Apr.
5
CHROMOBLASTOMYCOSIS: A NEGLECTED TROPICAL DISEASE.着色芽生菌病：一种被忽视的热带疾病。
Rev Inst Med Trop Sao Paulo. 2015 Sep;57 Suppl 19(Suppl 19):46-50. doi: 10.1590/S0036-46652015000700009.
6
Chromoblastomycosis caused by Phialophora verrucosa on the hand.由疣状瓶霉引起的手部着色芽生菌病。
Eur J Dermatol. 2015 May-Jun;25(3):274-5. doi: 10.1684/ejd.2015.2581.
7
Cutaneous Chromoblastomycosis Caused by Veronaea botryosa in a Patient with Pemphigus Vulgaris and Review of Published Reports.寻常型天疱疮患者并发葡萄穗霉引起的皮肤着色芽生菌病及已发表报告的综述
Mycopathologia. 2015 Aug;180(1-2):123-9. doi: 10.1007/s11046-015-9887-0. Epub 2015 Mar 31.
8
First reported Australian case of Cladophilophora arxii: features consistent with possible primary pulmonary chromoblastomycosis.首例澳大利亚枝孢黑粉菌病例报告：特征符合可能的原发性肺着色芽生菌病。
Am J Trop Med Hyg. 2015 Apr;92(4):791-3. doi: 10.4269/ajtmh.14-0711. Epub 2015 Jan 26.
9
Black yeasts and their filamentous relatives: principles of pathogenesis and host defense.黑色酵母菌及其丝状亲缘菌：发病机制与宿主防御原理
Clin Microbiol Rev. 2014 Jul;27(3):527-42. doi: 10.1128/CMR.00093-13.
10
A case of Exophiala spinifera infection in Southern Brazil: Molecular identification and antifungal susceptibility.巴西南部棘状外瓶霉感染病例：分子鉴定与抗真菌药敏分析
Med Mycol Case Rep. 2012 Sep 7;1(1):72-5. doi: 10.1016/j.mmcr.2012.08.006. eCollection 2012.

两性霉素 B 与特比萘芬联合治疗与着色真菌病相关的黑曲霉

Combination of Amphotericin B and Terbinafine against Melanized Fungi Associated with Chromoblastomycosis.

机构信息

Department of Medical Microbiology, People's Hospital of Suzhou National New & Hi-Tech Industrial Development Zone, Jiangsu, China.

Shanghai Institute of Medical Mycology, Department of Dermatology, Changzheng Hospital, Second Military Medical University, Shanghai, China.

出版信息

Antimicrob Agents Chemother. 2018 May 25;62(6). doi: 10.1128/AAC.00270-18. Print 2018 Jun.

DOI:10.1128/AAC.00270-18
PMID:29581111
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5971613/
Abstract

Our studies showed that a combination of amphotericin B and terbinafine had synergistic effects against the majority of melanized fungi associated with chromoblastomycosis (CBM) and similar infections, including those with , , , , , , , and This drug combination could provide an option for the treatment of severe or unresponsive cases of CBM, particularly in cases due to species of and .

摘要

我们的研究表明，两性霉素 B 和特比萘芬联合使用对大多数与着色芽生菌病（CBM）和类似感染相关的黑曲霉具有协同作用，包括 、 、 、 、 、 、 。这种药物联合治疗可能为治疗严重或对 CBM 反应不佳的病例提供一种选择，特别是由 和 引起的病例。