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1992 - 2009年北京老年人代谢综合征风险概况及其转变模式

Risk profiles for metabolic syndrome and its transition patterns for the elderly in Beijing, 1992-2009.

作者信息

Tao Li-Xin, Wang Wei, Zhu Hui-Ping, Huo Da, Zhou Tao, Pan Lei, Gao Qi, Luo Yan-Xia, Wu Li-Juan, Li Xia, Tang Zhe, Guo Xiu-Hua

机构信息

School of Public Health, Capital Medical University, 10 Xitoutiao, Youanmenwai, Fengtai, Beijing, 100069, China.

出版信息

Endocrine. 2014 Sep;47(1):161-8. doi: 10.1007/s12020-013-0143-4. Epub 2014 Jan 23.

Abstract

There have been few reports on the development of metabolic disorders, especially when they are considered as a cluster. The purpose of this study was to describe risk profiles for metabolic syndrome (MetS) in elderly dwellers in Beijing, and to find their transition patterns over time. Data were derived from Beijing longitudinal study of aging, a community-based cohort study hosted by Xuanwu hospital. There were 3,257 elderly people aged 55 years or over recruited in 1992. MetS was assessed for the years 1992, 2000, and 2009. Finally, 363 subjects with complete information for components of MetS in the three years were included in the study. The criteria of MetS recommended by the joint interim statement criteria were adopted. Latent transition analysis was used to calculate the transition probabilities between adjacent visits. A risk typology consisting of four time-invariant groups was detected based on the components of MetS for all subjects. Low MetS risk group, BP risk group, BP-HDL risk group, and BP-FPG-TG risk group were found. The probability of staying at the same status was higher at the two intervals across 18 years. Four latent groups were extracted based on three assessments for the components of MetS, together with their transition patterns. Findings suggested various trajectories for MetS components. Different combinations of intervention strategy might be needed for MetS risk groups.

摘要

关于代谢紊乱的发展,尤其是将其视为一个集群时的相关报道较少。本研究的目的是描述北京老年居民代谢综合征(MetS)的风险概况,并找出其随时间的转变模式。数据来自宣武医院开展的一项基于社区的队列研究——北京老龄化纵向研究。1992年招募了3257名55岁及以上的老年人。对1992年、2000年和2009年的代谢综合征进行了评估。最后,363名在这三年中拥有代谢综合征各组分完整信息的受试者被纳入研究。采用了联合临时声明标准推荐的代谢综合征标准。使用潜在转变分析来计算相邻访视之间的转变概率。基于所有受试者的代谢综合征组分检测到一个由四个时间不变组组成的风险类型。发现了低代谢综合征风险组、血压风险组、血压 - 高密度脂蛋白风险组和血压 - 空腹血糖 - 甘油三酯风险组。在18年的两个间隔期内,保持相同状态的概率较高。基于对代谢综合征组分的三次评估提取了四个潜在组及其转变模式。研究结果表明代谢综合征各组分存在不同轨迹。对于代谢综合征风险组可能需要不同的干预策略组合。

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