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2
Dietary sugars and body weight: systematic review and meta-analyses of randomised controlled trials and cohort studies.膳食糖与体重:随机对照试验和队列研究的系统评价和荟萃分析。
BMJ. 2012 Jan 15;346:e7492. doi: 10.1136/bmj.e7492.
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Changes in water and beverage intake and long-term weight changes: results from three prospective cohort studies.饮水量和饮料摄入量的变化与长期体重变化:三项前瞻性队列研究的结果。
Int J Obes (Lond). 2013 Oct;37(10):1378-85. doi: 10.1038/ijo.2012.225. Epub 2013 Jan 15.
4
Diet-obesity associations in children: approaches to counteract attenuation caused by misreporting.儿童饮食-肥胖关联:应对归因性偏误导致的衰减效应的方法。
Public Health Nutr. 2013 Feb;16(2):256-66. doi: 10.1017/S1368980012004491. Epub 2012 Oct 9.
5
A trial of sugar-free or sugar-sweetened beverages and body weight in children.含糖饮料和无糖饮料对儿童体重影响的临床试验。
N Engl J Med. 2012 Oct 11;367(15):1397-406. doi: 10.1056/NEJMoa1203034. Epub 2012 Sep 21.
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A randomized trial of sugar-sweetened beverages and adolescent body weight.含糖饮料与青少年体重的随机临床试验。
N Engl J Med. 2012 Oct 11;367(15):1407-16. doi: 10.1056/NEJMoa1203388. Epub 2012 Sep 21.
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Effect of fructose on body weight in controlled feeding trials: a systematic review and meta-analysis.果糖对控制喂养试验中体重的影响:系统评价和荟萃分析。
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Consumption of fried foods and weight gain in a Mediterranean cohort: the SUN project.食用油炸食品与地中海队列人群体重增加:SUN 项目。
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Changes in diet and lifestyle and long-term weight gain in women and men.女性和男性的饮食和生活方式改变与长期体重增加。
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Effects of 4-week very-high-fructose/glucose diets on insulin sensitivity, visceral fat and intrahepatic lipids: an exploratory trial.四周超高果糖/葡萄糖饮食对胰岛素敏感性、内脏脂肪和肝内脂肪的影响:一项探索性试验。
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含糖碳酸饮料的消费与儿童/青少年肥胖:一项病例对照研究。

Sugar-sweetened carbonated beverage consumption and childhood/adolescent obesity: a case-control study.

作者信息

Martin-Calvo Nerea, Martínez-González Miguel-Angel, Bes-Rastrollo Maira, Gea Alfredo, Ochoa Ma Carmen, Marti Amelia

机构信息

1Department of Preventive Medicine & Public Health,School of Medicine,University of Navarra,C/Irunlarrea 1,31008 Pamplona,Spain.

3Centro de Investigación Medica Aplicada (CIMA),Pamplona,Spain.

出版信息

Public Health Nutr. 2014 Oct;17(10):2185-93. doi: 10.1017/S136898001300356X. Epub 2014 Jan 31.

DOI:10.1017/S136898001300356X
PMID:24485091
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10282631/
Abstract

OBJECTIVE

To assess the association between the consumption of sugar-sweetened carbonated beverages (SSCB) and obesity in children and adolescents from Navarra (Spain).

DESIGN

We used a matched case-control study design. The exposure, SSCB consumption (1 serving: 200 ml), was measured with a previously validated FFQ. Anthropometrical measures were taken using standardized protocols. The outcome, obesity, was defined as BMI above the age- and sex-specific 97th percentile according to the Spanish reference charts. In the analysis we used conditional logistic regression. Potential confounders were controlled using a multivariable model.

SETTING

Subjects were recruited in the paediatric departments of the Universidad de Navarra Clinic and the Navarra Hospital Complex, and in three primary health centres of Navarra. Controls were recruited when attending for a routine medical examination or vaccination.

SUBJECTS

One hundred and seventy-four obese children and 174 individually sex- and age-matched controls, 52·87% boys, with a mean age of 11·6 years. Exclusion criteria were dietary interventions, exposure to hormone treatment, development of secondary obesity due to endocrinopathy and serious intercurrent illness.

RESULTS

Independently of other factors, high consumption of SSCB (>4 servings/week) was significantly associated with obesity (OR = 3·46; 95% CI 1·24, 9·62; P = 0·01). Besides, each additional daily serving of SSCB was associated with a 69% relative increase in the risk of obesity (OR = 1·69; 95% CI 1·04, 2·73; P = 0·03).

CONCLUSIONS

We found a strong and significant association between SSCB consumption and obesity risk. Our results suggest a monotonic dose-response linear shape for this association in children and adolescents (P for trend = 0·02).

摘要

目的

评估西班牙纳瓦拉地区儿童和青少年饮用含糖碳酸饮料(SSCB)与肥胖之间的关联。

设计

采用匹配病例对照研究设计。通过先前验证的食物频率问卷(FFQ)测量暴露因素,即SSCB的饮用量(1份:200毫升)。使用标准化方案进行人体测量。结局指标肥胖根据西班牙参考图表定义为体重指数(BMI)高于年龄和性别特异性的第97百分位数。在分析中,我们使用条件逻辑回归。通过多变量模型控制潜在混杂因素。

背景

研究对象在纳瓦拉大学诊所和纳瓦拉医院综合院区的儿科部门以及纳瓦拉的三个初级卫生中心招募。对照在进行常规体检或接种疫苗时招募。

研究对象

174名肥胖儿童和174名个体性别和年龄匹配的对照,男孩占52.87%,平均年龄11.6岁。排除标准包括饮食干预、接受激素治疗、因内分泌病导致继发性肥胖以及严重并发疾病。

结果

独立于其他因素,高SSCB饮用量(>4份/周)与肥胖显著相关(比值比[OR]=3.46;95%置信区间[CI]1.24,9.62;P=0.01)。此外,每天额外饮用一份SSCB与肥胖风险相对增加69%相关(OR=1.69;95%CI1.04,2.73;P=0.03)。

结论

我们发现饮用SSCB与肥胖风险之间存在强烈且显著的关联。我们的结果表明,在儿童和青少年中,这种关联呈单调剂量反应线性关系(趋势P值=0.02)。