Miki Emi, Kataoka Tsuyoshi, Okamura Hitoshi
Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan.
Psychooncology. 2014 Aug;23(8):906-13. doi: 10.1002/pon.3501. Epub 2014 Feb 14.
We conducted this study with the aim of demonstrating the feasibility and efficacy of speed-feedback therapy with a bicycle ergometer on cognitive function in elderly cancer patients.
The subjects were patients with breast or prostate cancer who were 65 years of age or over. Among 146 patients, 78 were randomly assigned to the intervention group (n = 38) or the control group (n = 40). The intervention group received speed-feedback therapy with a bicycle ergometer once a week for four successive weeks. The control group was advised to spend the 4-week period engaged in their routine activities. Evaluations were carried out at the baseline and 4 weeks after the baseline (week 4) using the Frontal Assessment Battery, the Barthel Index, the Lawton and Brody Instrumental Activities of Daily Living, and the Functional Assessment of Cancer Therapy-General ver.4. Data were analyzed by a two-way repeated-measures analysis of variance.
The mean score of Frontal Assessment Battery for the intervention group was higher than that for the control group at week 4. In addition to significant main effects of time and group, we also found a significant interaction between the two groups (p = 0.006). Moreover, all of the subjects in the intervention group could complete all the four sessions of therapy without any pain or distress.
These results suggest that speed-feedback therapy with a bicycle ergometer may be feasible as well as effective for improving the cognitive function in elderly cancer patients.
我们开展本研究旨在证明使用自行车测力计进行速度反馈疗法对老年癌症患者认知功能的可行性和有效性。
研究对象为65岁及以上的乳腺癌或前列腺癌患者。在146例患者中，78例被随机分配至干预组（n = 38）或对照组（n = 40）。干预组每周使用自行车测力计进行一次速度反馈疗法，连续四周。对照组被建议在四周内进行日常活动。在基线期以及基线期后4周（第4周）使用简易精神状态检查表、巴氏指数、洛顿和布罗迪日常生活能力量表以及癌症治疗功能评估通用版第4版进行评估。采用双向重复测量方差分析对数据进行分析。
在第4周时，干预组简易精神状态检查表的平均得分高于对照组。除了时间和组别的显著主效应外，我们还发现两组之间存在显著交互作用（p = 0.006）。此外，干预组的所有受试者均能完成全部四节治疗课程，且无任何疼痛或不适。
这些结果表明，使用自行车测力计进行速度反馈疗法对于改善老年癌症患者的认知功能可能既可行又有效。
