Lee Hyun Seok, Jeon Seong Woo
Department of Internal Medicine, Kyungpook National University Hospital, Kyungpook National University School of Medicine, Daegu, Korea.
Clin Endosc. 2014 Jan;47(1):15-22. doi: 10.5946/ce.2014.47.1.15. Epub 2014 Jan 24.
Barrett esophagus (BE) is considered to develop as a result of chronic gastroesophageal reflux disease (GERD) and to predispose to esophageal adenocarcinoma (EAC). However, the disease pattern of BE in Asia differs from that observed in the West. For example, in the West, the prevalence rates of BE and EAC have progressively increased, whereas although the prevalence rate of GERD is increasing in Asia, the prevalence rates of BE and EAC have remained low in most Asian countries. GERD, hiatal hernia, old age, male sex, abdominal obesity (visceral obesity), smoking, alcohol consumption, and kyphosis are known risk factors for BE in Asia, and most Asian patients have short-segment BE. Helicobacter pylori infection is more prevalent in Asia than in the West. We suggest larger studies with a prospective design be conducted to elaborate further the different patterns of BE in Asia.
巴雷特食管（BE）被认为是由慢性胃食管反流病（GERD）发展而来，并易患食管腺癌（EAC）。然而，亚洲BE的疾病模式与西方观察到的不同。例如，在西方，BE和EAC的患病率逐渐上升，而尽管亚洲GERD的患病率在增加，但在大多数亚洲国家，BE和EAC的患病率仍然较低。GERD、食管裂孔疝、老年、男性、腹部肥胖（内脏肥胖）、吸烟、饮酒和脊柱后凸是亚洲BE已知的危险因素，并且大多数亚洲患者为短段BE。幽门螺杆菌感染在亚洲比在西方更普遍。我们建议进行更大规模的前瞻性研究，以进一步阐明亚洲BE的不同模式。
