Gahalaut Pratik, Mishra Nitin, Chauhan Sandhya, Rastogi Madhur Kant
Department of Dermatology, Venereology and Leprosy, Shri Ram Murti Smarak Institute of Medical Sciences, Nainital Road, Bareilly 243001, India.
Department of Pediatrics, Shri Ram Murti Smarak Institute of Medical Sciences, Nainital Road, Bareilly 243001, India.
ISRN Dermatol. 2014 Jan 29;2014:743027. doi: 10.1155/2014/743027. eCollection 2014.
Introduction. Topical application of local anesthetics is currently considered to be the easiest, most effective, and convenient way for treatment of patients who may be undergoing superficial dermatosurgical procedures. Materials and Methods. This study compares the anesthetic potential of 2.5% lidocaine and 2.5% prilocaine topical cream with 7% lignocaine and 7% tetracaine combination cream for radio ablative dermatosurgery when applied, under occlusion, for 30 minutes. 40 subjects of achrocordons were enrolled in this split-side randomized trial. Result. The pain severity experienced by subjects in terms of visual analogue scale score was significantly lesser for lignocaine/tetracaine combination cream as compared to lidocaine/prilocaine combination. Conclusion. This small study proves the efficacy of lidocaine/tetracaine combination as a topical anesthetic cream when applied for a short time interval of 30 minutes. This will help a dermatosurgeon to perform various dermatological procedures in a better and efficient manner with a shorter waiting period for analgesia to set in.
引言。目前，局部麻醉剂的局部应用被认为是治疗可能正在接受浅表皮肤外科手术患者的最简单、最有效且最便捷的方法。材料与方法。本研究比较了2.5%利多卡因和2.5%丙胺卡因外用乳膏与7%利多卡因和7%丁卡因复方乳膏在闭塞条件下应用30分钟时用于放射性皮肤外科手术的麻醉潜力。40名患有皮赘的受试者参与了这项双侧随机试验。结果。与利多卡因/丙胺卡因复方相比，利多卡因/丁卡因复方乳膏使受试者在视觉模拟量表评分方面所经历的疼痛严重程度明显更低。结论。这项小型研究证明了利多卡因/丁卡因复方作为外用麻醉乳膏在30分钟短时间应用时的有效性。这将有助于皮肤科医生以更好、更高效的方式进行各种皮肤科手术，且镇痛起效的等待时间更短。
