Wells Kristen J, Arevalo Mariana, Meade Cathy D, Gwede Clement K, Quinn Gwendolyn P, Luque John S, San Miguel Gloria, Watson Dale, Phillips Rebecca, Reyes Carmen, Romo Margarita, West Jim, Jacobsen Paul B
Authors' Affiliations: San Diego State University; Moore's Cancer Center, San Diego, California; University of Texas Health Sciences Center, Houston, Texas; Moffitt Cancer Center; University of South Florida, Tampa; Morton Plant Mease Healthcare, Clearwater; Florida Department of Health, St. Petersburg; Farmworkers Self-Help, Dade City; JWest Prostate Cancer Foundation, St. Petersburg, Florida; Georgia Southern University, Statesboro, Georgia; and Multicultural Resource Center, Inc., Seffner, Florida.
Cancer Epidemiol Biomarkers Prev. 2014 Mar;23(3):374-82. doi: 10.1158/1055-9965.EPI-13-0746.
No validated multiscale instruments exist that measure community members' views on biobanking and biospecimen donation. This study describes the development and psychometric properties of the English-language BANKS (Biobanking Attitudes and Knowledge Survey).
The BANKS was created by item generation through review of scientific literature, focus groups with community members, and input from a community advisory board. Items were refined through cognitive interviews. Content validity was assessed through an expert panel review. Psychometric properties of the BANKS were assessed in a sample of 85 community members.
The final BANKS includes three scales: attitudes, knowledge, and self-efficacy; as well as three single items, which evaluated receptivity and intention to donate a biospecimen for research. Cronbach α coefficients for two scales that use Likert response format indicated high internal consistency (attitudes: α, 0.88; self-efficacy: α, 0.95). Content validity indices were moderate, ranging from 0.69 to 0.89. Intention to donate blood and intention to donate urine were positively correlated with attitudes, knowledge, self-efficacy, and receptivity to learning more about biobanking (P values range from 0.029 to <0.001).
The final BANKS shows evidence of satisfactory reliability and validity, is easy to administer, and is a promising tool to inform biospecimen research. Additional studies should be conducted with larger samples considering biospecimen donation to further assess the reliability and validity of the instrument.
A valid and reliable instrument measuring community members' views about biobanking may help researchers evaluate relevant communication interventions to enhance understanding, intention, and actual biospecimen donation. A Spanish-language BANKS is under development.
目前尚无经过验证的多尺度工具来衡量社区成员对生物样本库和生物样本捐赠的看法。本研究描述了英语版BANKS（生物样本库态度与知识调查）的开发过程及其心理测量特性。
通过回顾科学文献、与社区成员进行焦点小组讨论以及社区咨询委员会的意见来生成BANKS的项目。通过认知访谈对项目进行完善。通过专家小组评审评估内容效度。在85名社区成员的样本中评估BANKS的心理测量特性。
最终的BANKS包括三个量表：态度、知识和自我效能感；以及三个单项，用于评估对为研究捐赠生物样本的接受度和意愿。使用李克特量表回答格式的两个量表的克朗巴赫α系数表明内部一致性较高（态度：α = 0.88；自我效能感：α = 0.95）。内容效度指数中等，范围从0.69到0.89。献血意愿和捐尿意愿与态度、知识、自我效能感以及对了解更多生物样本库信息的接受度呈正相关（P值范围从0.029到<0.001）。
最终的BANKS显示出令人满意的信度和效度证据，易于实施，是用于生物样本研究的一个有前景的工具。应使用更大样本并考虑生物样本捐赠进行更多研究，以进一步评估该工具的信度和效度。
一个有效且可靠的测量社区成员对生物样本库看法的工具可能有助于研究人员评估相关的沟通干预措施，以增强理解、意愿和实际的生物样本捐赠。西班牙语版的BANKS正在开发中。
