Moghbel Abdolhossein, Farjzadeh Ahmad, Aghel Nasrin, Agheli Homaun, Raisi Nafiseh
Department of Pharmaceutics, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran.
Department of Microbiology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran.
Jundishapur J Nat Pharm Prod. 2012 Spring;7(2):56-60. Epub 2012 May 28.
Compounds present in green tea have proved to inhibit the growth and activity of bacteria associated with infections.
To assess the effects of green tea leaves extract in presence of propylene glycol on the aerobic mouth bacteria load.
Saliva of 25 volunteer girl students aging 20-25 years were selected and evaluated by a mouthwash sample containing 1% tannin, as the most effective antibacterial complex in green tea. Comparative studies were also conducted between green tea mouthwashes containing 1% tannin and a similar sample with 10% propylene glycol added during extraction. This comparison was applied for a chlorhexidine 0.2% sample as a chemical mouthwash brand, too.
There was a meaningful difference between the green tea mouthwashes containing 10% propylene glycol and the simple green tea extract (P < 0.05). Significant difference was also seen between the herbal and chemical mouthwashes (P < 0.05). The extract 1% tannin containing 10% propylene glycol reduced the aerobic mouth bacterial load of the student salvia about 64 percent. The pH monotonousness in different days and temperatures approved the stability of tannin in liquid water medium.
Using green tea extract as a herbal mouthwash is safe and harmless specially for children and pregnant women. This result led us to suppose that green tea may prevent plaque formation on teeth, coming over halitosis due to mouth infection, too. These effects need to be approved in an in vivo trial as a second study.
绿茶中的化合物已被证明可抑制与感染相关细菌的生长和活性。
评估在丙二醇存在下绿茶提取物对口腔需氧菌负荷的影响。
选取25名年龄在20 - 25岁的女大学生志愿者的唾液,用含有1%单宁的漱口水样本进行评估,单宁是绿茶中最有效的抗菌复合物。还对含有1%单宁的绿茶漱口水与在提取过程中添加了10%丙二醇的类似样本进行了比较研究。这种比较也适用于0.2%洗必泰样本作为化学漱口水品牌。
含有10%丙二醇的绿茶漱口水与单纯绿茶提取物之间存在显著差异(P < 0.05)。草药漱口水和化学漱口水之间也存在显著差异(P < 0.05)。含有10%丙二醇的1%单宁提取物使学生唾液中的口腔需氧菌负荷降低了约64%。不同日期和温度下的pH稳定性证实了单宁在液态水介质中的稳定性。
使用绿茶提取物作为草药漱口水对儿童和孕妇特别安全无害。这一结果使我们推测绿茶可能预防牙齿上的牙菌斑形成,也可消除因口腔感染引起的口臭。这些效果需要在第二项体内试验研究中得到证实。