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使用双切换系统和可分离集束电极的单极射频消融:体内效率评估。

Monopolar radiofrequency ablation using a dual-switching system and a separable clustered electrode: evaluation of the in vivo efficiency.

机构信息

Department of Radiology, Seoul National University Hospital, Seoul 110-744, Korea.

Department of Radiology, Seoul National University Hospital, Seoul 110-744, Korea. ; Institute of Radiation Medicine, Seoul National University College of Medicine, Seoul 110-744, Korea.

出版信息

Korean J Radiol. 2014 Mar-Apr;15(2):235-44. doi: 10.3348/kjr.2014.15.2.235. Epub 2014 Mar 7.

DOI:10.3348/kjr.2014.15.2.235
PMID:24643383
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3955790/
Abstract

OBJECTIVE

To determine the in vivo efficiency of monopolar radiofrequency ablation (RFA) using a dual-switching (DS) system and a separable clustered (SC) electrode to create coagulation in swine liver.

MATERIALS AND METHODS

Thirty-three ablation zones were created in nine pigs using a DS system and an SC electrode in the switching monopolar mode. The pigs were divided into two groups for two experiments: 1) preliminary experiments (n = 3) to identify the optimal inter-electrode distances (IEDs) for dual-switching monopolar (DSM)-RFA, and 2) main experiments (n = 6) to compare the in vivo efficiency of DSM-RFA with that of a single-switching monopolar (SSM)-RFA. RF energy was alternatively applied to one of the three electrodes (SSM-RFA) or concurrently applied to a pair of electrodes (DSM-RFA) for 12 minutes in in vivo porcine livers. The delivered RFA energy and the shapes and dimensions of the coagulation areas were compared between the two groups.

RESULTS

No pig died during RFA. The ideal IEDs for creating round or oval coagulation area using the DSM-RFA were 2.0 and 2.5 cm. DSM-RFA allowed more efficient RF energy delivery than SSM-RFA at the given time (23.0 ± 4.0 kcal vs. 16.92 ± 2.0 kcal, respectively; p = 0.0005). DSM-RFA created a significantly larger coagulation volume than SSM-RFA (40.4 ± 16.4 cm(3) vs. 20.8 ± 10.7 cm(3); p < 0.001). Both groups showed similar circularity of the ablation zones (p = 0.29).

CONCLUSION

Dual-switching monopolar-radiofrequency ablation using an SC electrode is feasible and can create larger ablation zones than SSM-RFA as it allows more RF energy delivery at a given time.

摘要

目的

使用双开关(DS)系统和可分离集簇(SC)电极,在猪肝中确定单极射频消融(RFA)的体内效率。

材料与方法

使用 DS 系统和 SC 电极在开关单极模式下,在 9 只猪中创建了 33 个消融区。这些猪分为两组进行两项实验:1)初步实验(n=3),以确定双开关单极(DSM)-RFA 的最佳电极间距离(IED),2)主要实验(n=6),比较 DSM-RFA 与单开关单极(SSM)-RFA 的体内效率。在活体猪肝中,交替为三个电极中的一个(SSM-RFA)或同时为一对电极(DSM-RFA)施加射频能量 12 分钟。比较两组之间的消融区形状和尺寸以及输送的 RFA 能量。

结果

在 RFA 期间没有猪死亡。使用 DSM-RFA 形成圆形或椭圆形消融区的理想 IED 为 2.0 和 2.5cm。在给定时间内,DSM-RFA 比 SSM-RFA 能更有效地输送 RF 能量(分别为 23.0±4.0 卡路里和 16.92±2.0 卡路里;p=0.0005)。DSM-RFA 形成的凝固体积明显大于 SSM-RFA(40.4±16.4cm3 与 20.8±10.7cm3;p<0.001)。两组的消融区均具有相似的圆形度(p=0.29)。

结论

使用 SC 电极的双开关单极-RFA 是可行的,并且可以比 SSM-RFA 形成更大的消融区,因为它可以在给定时间内输送更多的 RF 能量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00ca/3955790/e64ee10d6f49/kjr-15-235-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00ca/3955790/afa9c24bc0c2/kjr-15-235-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00ca/3955790/ce3f4d7219a5/kjr-15-235-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00ca/3955790/e14fe6796383/kjr-15-235-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00ca/3955790/e64ee10d6f49/kjr-15-235-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00ca/3955790/afa9c24bc0c2/kjr-15-235-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00ca/3955790/ce3f4d7219a5/kjr-15-235-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00ca/3955790/e14fe6796383/kjr-15-235-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00ca/3955790/e64ee10d6f49/kjr-15-235-g004.jpg

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