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塞内加尔的流感样疾病:不仅仅关注流感病毒。

Influenza-like illnesses in Senegal: not only focus on influenza viruses.

作者信息

Dia Ndongo, Diene Sarr Fatoumata, Thiam Diamilatou, Faye Sarr Tening, Espié Emmanuelle, OmarBa Ibrahim, Coly Malang, Niang Mbayame, Richard Vincent

机构信息

Virological Unit, Pasteur Institute in Dakar, Dakar, Senegal.

Epidemiology Unit, Pasteur Institute in Dakar, Dakar, Senegal.

出版信息

PLoS One. 2014 Mar 27;9(3):e93227. doi: 10.1371/journal.pone.0093227. eCollection 2014.

Abstract

Influenza surveillance in African countries was initially restricted to the identification of circulating strains. In Senegal, the network has recently been enhanced (i) to include epidemiological data from Dakar and other regions and (ii) to extend virological surveillance to other respiratory viruses. Epidemiological data from the sentinel sites is transmitted daily by mobile phone. The data include those for other febrile syndromes similar to influenza-like illnesses (ILI), corresponding to integrated approach. Also, clinical samples are randomly selected and analyzed for influenza and other respiratory viruses. There were 101,640 declared visits to the 11 sentinel sites between week 11-2012 and week 35-2013; 22% of the visits were for fever syndromes and 23% of the cases of fever syndrome were ILI. Influenza viruses were the second most frequent cause of ILI (20%), after adenoviruses (21%) and before rhinoviruses (18%) and enteroviruses (15%). Co-circulation and co-infection were frequent and were responsible for ILI peaks. The first months of implementation of the enhanced surveillance system confirmed that viruses other the influenza make large contributions to influenza-like illnesses. It is therefore important to consider these etiologies in the development of strategies to reduce respiratory infections. More informative tools and research studies are required to assess the burden of respiratory infections in developing countries.

摘要

非洲国家的流感监测最初仅限于识别流行毒株。在塞内加尔,该监测网络最近得到了加强:(i)纳入了来自达喀尔和其他地区的流行病学数据;(ii)将病毒学监测扩展到其他呼吸道病毒。哨点的流行病学数据每天通过手机传输。这些数据包括与流感样疾病(ILI)相似的其他发热综合征的数据,这符合综合方法。此外,还随机选取临床样本,对流感和其他呼吸道病毒进行分析。在2012年第11周和2013年第35周期间,11个哨点共记录了101,640次就诊;其中22%的就诊是因发热综合征,而发热综合征病例中有23%为流感样疾病。流感病毒是流感样疾病的第二大常见病因(20%),仅次于腺病毒(21%),排在鼻病毒(18%)和肠道病毒(15%)之前。病毒的共同流行和共同感染很常见,是导致流感样疾病高峰的原因。强化监测系统实施的头几个月证实,除流感病毒外,其他病毒对流感样疾病也有很大影响。因此,在制定减少呼吸道感染的策略时,考虑这些病因很重要。需要更具信息性的工具和研究来评估发展中国家呼吸道感染的负担。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d99/3968133/29ac8a364406/pone.0093227.g001.jpg

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