J Surg Oncol. 2014 Mar;109(4):301-7. doi: 10.1002/jso.23512.
Superficially metastatic melanoma still represents a challenging situation for oncologists and a distressing condition for patients. In this circumstance, local treatment by electrochemotherapy, that is, the combination of brief permeabilizing electric pulses with a low‐toxicity anticancer drug, can be a valuable treatment option in selected patients who are ineligible/refractory to systemic treatments or require rapid palliation of symptomatic cutaneous disease.
对于肿瘤学家来说,表面转移性黑色素瘤仍然是一个具有挑战性的情况,对患者来说也是一种痛苦的状况。在这种情况下,电化疗的局部治疗,即短暂的通透性电脉冲与低毒性抗癌药物的联合应用,对于那些不适合/不耐受全身治疗或需要迅速缓解症状性皮肤疾病的选择患者来说,是一种有价值的治疗选择。