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广泛氩激光光凝治疗增殖性糖尿病视网膜病变

Extensive argon laser photocoagulation in the treatment of proliferative diabetic retinopathy.

作者信息

Aylward G W, Pearson R V, Jagger J D, Hamilton A M

机构信息

Moorfields Eye Hospital, London.

出版信息

Br J Ophthalmol. 1989 Mar;73(3):197-201. doi: 10.1136/bjo.73.3.197.

DOI:10.1136/bjo.73.3.197
PMID:2468355
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1041690/
Abstract

A group of 20 patients (28 eyes) with proliferative retinopathy who required extensive argon laser photocoagulation to induce regression of new vessels is presented. The mean number of burns applied to each eye was 7225, with a maximum of 11,513. These were delivered in a mean of nine sessions over a mean period of 22.9 months. Twenty-five eyes (89%) had a final visual acuity of 6/18 or better. The remaining three eyes (11%) had severely reduced vision attributable to complications of proliferative diabetic retinopathy (traction retinal detachment involving the macula in two eyes and ischaemic maculopathy and a persistent vitreous haemorrhage in the third). Large amounts of confluent argon laser photocoagulation may be necessary for the elimination of new vessels in some patients, and it is our view that laser photocoagulation should be continued until regression of new vessels occurs. This is compatible with the retention of functional vision and good visual acuity.

摘要

本文报告了一组20例(28只眼)增生性视网膜病变患者,这些患者需要进行广泛的氩激光光凝以促使新生血管消退。每只眼接受的平均烧灼点数为7225个,最多为11513个。这些烧灼点平均分9次进行,历时平均22.9个月。25只眼(89%)最终视力达到6/18或更好。其余3只眼(11%)视力严重下降,原因是增生性糖尿病视网膜病变的并发症(两只眼黄斑区发生牵拉性视网膜脱离,第三只眼出现缺血性黄斑病变和持续性玻璃体积血)。对于某些患者,可能需要大量融合的氩激光光凝来消除新生血管,我们认为应持续进行激光光凝,直到新生血管消退。这与保留功能性视力和良好的视敏度是相符的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/03c4/1041690/5e83e620b90e/brjopthal00595-0042-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/03c4/1041690/5e83e620b90e/brjopthal00595-0042-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/03c4/1041690/5e83e620b90e/brjopthal00595-0042-a.jpg

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本文引用的文献

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PDR in juvenile onset diabetics: high-risk proliferative diabetic retinopathy in juvenile onset diabetics.青少年起病型糖尿病患者的增殖性糖尿病视网膜病变:青少年起病型糖尿病患者的高危增殖性糖尿病视网膜病变
Retina. 1981;1(1):18-26.
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Estimation of the maximum number of argon laser burns possible in panretinal photocoagulation.全视网膜光凝中可能的氩激光烧伤最大数量的估计。
Am J Ophthalmol. 1984 Jun;97(6):697-703. doi: 10.1016/0002-9394(84)90500-2.
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Single versus multiple treatment sessions of argon laser panretinal photocoagulation for proliferative diabetic retinopathy.
帕斯卡全视网膜激光光凝术和增生性糖尿病视网膜病变的回归分析:曼彻斯特帕斯卡研究报告 4。
Eye (Lond). 2011 Nov;25(11):1447-56. doi: 10.1038/eye.2011.188. Epub 2011 Aug 5.
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Intravitreal Bevacizumab (Avastin) for Diabetic Retinopathy: The 2010 GLADAOF Lecture.玻璃体内注射贝伐单抗(阿瓦斯汀)治疗糖尿病性视网膜病变:2010年格拉多夫讲座
J Ophthalmol. 2011;2011:584238. doi: 10.1155/2011/584238. Epub 2011 Mar 30.
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Intracameral bevacizumab and mitomycin C Trabeculectomy for eyes with neovascular glaucoma: a case series.前房内注射贝伐单抗与丝裂霉素C小梁切除术治疗新生血管性青光眼:病例系列
J Ocul Biol Dis Infor. 2009 Mar 31;2(1):40-6. doi: 10.1007/s12177-009-9020-z.
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A proposed new classification for diabetic retinopathy: the concept of primary and secondary vitreopathy.糖尿病视网膜病变的一种新提议分类:原发性和继发性玻璃体病变的概念。
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Characterisation of the neovascularisation process in diabetic retinopathy by means of fractal geometry: diagnostic implications.通过分形几何表征糖尿病视网膜病变中的新生血管形成过程:诊断意义
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7
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