Golz R, Schubert G E
Institute of Pathology, Municipal Hospital of Wuppertal, Federal Republic of Germany.
J Urol. 1989 Jun;141(6):1480-2. doi: 10.1016/s0022-5347(17)41351-6.
Urachal remnants were obtained at autopsy from 10 males and 15 females in order to determine whether prostatic specific antigen (PSA) is present in that tissue. Immunohistochemical staining was carried out using a commercially available antibody to PSA. Four cases (three females and one male) showed focal positive reaction of PSA, predominantly in narrow glandular structures of metaplastic origin. Therefore, it cannot be excluded that PSA might occur in urachal adenocarcinomas. PSA-staining is evidently not confined exclusively to tissue originating in the prostate.
为了确定前列腺特异性抗原（PSA）是否存在于脐尿管残余组织中，我们从10名男性和15名女性的尸检中获取了脐尿管残余组织。使用市售的PSA抗体进行免疫组织化学染色。4例（3例女性和1例男性）显示PSA呈局灶性阳性反应，主要位于化生来源的狭窄腺管结构中。因此，不能排除PSA可能出现在脐尿管腺癌中。PSA染色显然并不局限于起源于前列腺的组织。
