Bang L T, Long B D, Othman R
Rekagraf Laboratory, School of Materials and Mineral Resources Engineering, Universiti Sains Malaysia, 14300 Nibong Tebal, Malaysia.
Department of Mechanical Engineering, Faculty of Engineering, University of Malaya, 50603 Kuala Lumpur, Malaysia.
ScientificWorldJournal. 2014 Mar 2;2014:969876. doi: 10.1155/2014/969876. eCollection 2014.
The present study investigates the chemical composition, solubility, and physical and mechanical properties of carbonate hydroxyapatite (CO3Ap) and silicon-substituted carbonate hydroxyapatite (Si-CO3Ap) which have been prepared by a simple precipitation method. X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), X-ray fluorescence (XRF) spectroscopy, and inductively coupled plasma (ICP) techniques were used to characterize the formation of CO3Ap and Si-CO3Ap. The results revealed that the silicate (SiO4(4-)) and carbonate (CO3(2-)) ions competed to occupy the phosphate (PO4(3-)) site and also entered simultaneously into the hydroxyapatite structure. The Si-substituted CO3Ap reduced the powder crystallinity and promoted ion release which resulted in a better solubility compared to that of Si-free CO3Ap. The mean particle size of Si-CO3Ap was much finer than that of CO3Ap. At 750°C heat-treatment temperature, the diametral tensile strengths (DTS) of Si-CO3Ap and CO3Ap were about 10.8 ± 0.3 and 11.8 ± 0.4 MPa, respectively.
本研究调查了通过简单沉淀法制备的碳酸羟基磷灰石（CO3Ap）和硅取代碳酸羟基磷灰石（Si-CO3Ap）的化学成分、溶解性以及物理和机械性能。采用X射线衍射（XRD）、傅里叶变换红外光谱（FTIR）、X射线荧光（XRF）光谱和电感耦合等离子体（ICP）技术对CO3Ap和Si-CO3Ap的形成进行了表征。结果表明，硅酸根（SiO4(4-)）和碳酸根（CO3(2-)）离子竞争占据磷酸根（PO4(3-)）位点，并且还同时进入羟基磷灰石结构。与不含硅的CO3Ap相比，硅取代的CO3Ap降低了粉末结晶度并促进了离子释放，从而具有更好的溶解性。Si-CO3Ap的平均粒径比CO3Ap细得多。在750°C的热处理温度下，Si-CO3Ap和CO3Ap的径向拉伸强度（DTS）分别约为10.8±0.3和11.8±0.4 MPa。
