Micco Jamie A, Henin Aude, Hirshfeld-Becker Dina R
Child Cognitive Behavioral Therapy Program, Massachusetts General Hospital and Harvard Medical School.
Cognit Ther Res. 2014 Apr 1;38(2):89-102. doi: 10.1007/s10608-013-9578-4.
This study evaluated the efficacy of a four-session Cognitive Bias Modification-Interpretation program for 45 depressed adolescents and young adults (14-21 years old; 12 males, 33 females; Beck Depressive Inventory, Second Edition ≥ 14) randomized to an active intervention condition (repeated exposure to positive outcomes of depression-relevant ambiguous scenarios; n=23) or a control condition (n=22). Both conditions experienced reductions on a Test of Interpretation Bias at post-treatment, with no significant between-group differences. When limited to those with negative bias at baseline, the intervention group showed greater improvement in interpretation bias at mid- and post-treatment. In addition, the intervention group overall had greater improvements in self-reported negative cognitions than the control group at post-intervention and two-week follow-up. However, there were no differences between groups in depression or anxiety symptom change. Potential factors contributing to mixed findings are discussed.
本研究评估了一个为期四节的认知偏差修正-解释项目对45名抑郁青少年和青年（14至21岁；12名男性，33名女性；贝克抑郁量表第二版≥14）的疗效，这些参与者被随机分配到积极干预组（反复接触与抑郁相关的模糊情景的积极结果；n=23）或对照组（n=22）。两组在治疗后对解释偏差测试的结果都有所降低，组间无显著差异。当仅限于基线时有负偏差的参与者时，干预组在治疗中期和后期的解释偏差改善更大。此外，干预组在干预后和两周随访时，自我报告的消极认知总体上比对照组有更大改善。然而，两组在抑郁或焦虑症状变化方面没有差异。本文讨论了导致结果不一的潜在因素。
