• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

良性关节过度活动综合征患者中疼痛是唯一症状吗?

Is pain the only symptom in patients with benign joint hypermobility syndrome?

作者信息

Albayrak İlknur, Yilmaz Halim, Akkurt Halil Ekrem, Salli Ali, Karaca Gülten

机构信息

Department of Physical Medicine and Rehabilitation, Medical School of Selcuk University, Konya, Turkey,

出版信息

Clin Rheumatol. 2015 Sep;34(9):1613-9. doi: 10.1007/s10067-014-2610-6. Epub 2014 Apr 18.

DOI:10.1007/s10067-014-2610-6
PMID:24744155
Abstract

The aims of this study were to evaluate pain, depression level, fatigue, sleep, and quality of life (QoL) among patients with benign joint hypermobility syndrome (BJHS) and to compare their results with those of healthy controls. The study involved 115 patients and 114 healthy volunteers. Pain level was rated using visual analogue scale (VAS) for all patients. Depression level, fatigue, sleep quality, and QoL of all the participants were evaluated by the Beck Depression Inventory (BDI), the Checklist Individual Strength (CIS), the Pittsburgh Sleep Quality Index (PSQI), and the Short Form-36 (SF-36), respectively. VAS value was 6.29 ± 0.94 in the patient group. Comparison of two groups showed that there were statistically significant differences between the patient group and the control group with respect to BDI, total CIS, PSQI scores, SF-36 subscales (physical function, role physical, bodily pain, general health, role emotional, and mental health), and mental component summary (p < 0.001). While pain is the predominant symptom among BJHS patients, depression, fatigue, impaired sleep, and QoL also commonly occur. Thus, all of these components should be taken into account when assessing patients with BJHS.

摘要

本研究的目的是评估良性关节过度活动综合征(BJHS)患者的疼痛、抑郁水平、疲劳、睡眠和生活质量(QoL),并将其结果与健康对照组进行比较。该研究纳入了115例患者和114名健康志愿者。所有患者均使用视觉模拟量表(VAS)对疼痛程度进行评分。所有参与者的抑郁水平、疲劳、睡眠质量和生活质量分别通过贝克抑郁量表(BDI)、个人力量清单(CIS)、匹兹堡睡眠质量指数(PSQI)和简明健康调查问卷36项量表(SF-36)进行评估。患者组的VAS值为6.29±0.94。两组比较显示,患者组与对照组在BDI、CIS总分、PSQI评分、SF-36分量表(身体功能、角色身体、身体疼痛、总体健康、角色情感和心理健康)以及心理成分总结方面存在统计学显著差异(p<0.001)。虽然疼痛是BJHS患者的主要症状,但抑郁、疲劳、睡眠障碍和生活质量也很常见。因此,在评估BJHS患者时应考虑所有这些因素。

相似文献

1
Is pain the only symptom in patients with benign joint hypermobility syndrome?良性关节过度活动综合征患者中疼痛是唯一症状吗?
Clin Rheumatol. 2015 Sep;34(9):1613-9. doi: 10.1007/s10067-014-2610-6. Epub 2014 Apr 18.
2
Assessment of pain, care burden, depression level, sleep quality, fatigue and quality of life in the mothers of children with cerebral palsy.对脑瘫患儿母亲的疼痛、护理负担、抑郁程度、睡眠质量、疲劳及生活质量的评估。
J Child Health Care. 2019 Sep;23(3):483-494. doi: 10.1177/1367493519864751. Epub 2019 Jul 18.
3
Autonomic symptom burden in the hypermobility type of Ehlers-Danlos syndrome: a comparative study with two other EDS types, fibromyalgia, and healthy controls.自主症状负担在 Ehlers-Danlos 综合征高活动型中:与另外两种 EDS 类型、纤维肌痛和健康对照组的比较研究。
Semin Arthritis Rheum. 2014 Dec;44(3):353-61. doi: 10.1016/j.semarthrit.2014.05.013. Epub 2014 May 14.
4
Pain, depression levels, fatigue, sleep quality, and quality of life in elderly patients with rheumatoid arthritis.类风湿关节炎老年患者的疼痛、抑郁水平、疲劳、睡眠质量和生活质量。
Turk J Med Sci. 2017 Jun 12;47(3):847-853. doi: 10.3906/sag-1603-147.
5
Low- and high-anxious hypermobile Ehlers-Danlos syndrome patients: comparison of psychosocial and health variables.低焦虑和高焦虑型易发性埃勒斯-当洛斯综合征患者:心理社会和健康变量的比较。
Rheumatol Int. 2018 May;38(5):871-878. doi: 10.1007/s00296-018-4003-7. Epub 2018 Mar 1.
6
Features that exacerbate fatigue severity in joint hypermobility syndrome/Ehlers-Danlos syndrome - hypermobility type.关节过度活动综合征/埃勒斯-当洛综合征-过度活动型中加剧疲劳严重程度的特征。
Disabil Rehabil. 2018 Aug;40(17):1989-1996. doi: 10.1080/09638288.2017.1323022. Epub 2017 May 9.
7
Orthostatic intolerance and fatigue in the hypermobility type of Ehlers-Danlos Syndrome.埃勒斯-当洛综合征高活动型中的直立不耐受和疲劳
Rheumatology (Oxford). 2016 Aug;55(8):1412-20. doi: 10.1093/rheumatology/kew032. Epub 2016 Apr 18.
8
Unexpected association between joint hypermobility syndrome/Ehlers-Danlos syndrome hypermobility type and obsessive-compulsive personality disorder.关节过度活动综合征/埃勒斯-当洛综合征过度活动型与强迫型人格障碍之间的意外关联。
Rheumatol Int. 2014 May;34(5):631-6. doi: 10.1007/s00296-013-2901-2. Epub 2013 Nov 23.
9
Psychiatric symptoms in ankylosing spondylitis: their relationship with disease activity, functional capacity, pain and fatigue.强直性脊柱炎的精神症状:与疾病活动度、功能能力、疼痛和疲劳的关系。
Compr Psychiatry. 2015 Oct;62:170-7. doi: 10.1016/j.comppsych.2015.07.016. Epub 2015 Jul 29.
10
Correlation between benign joint hypermobility syndrome and headache in children and adolescents.儿童和青少年良性关节过度活动综合征与头痛的相关性。
BMC Musculoskelet Disord. 2024 May 2;25(1):347. doi: 10.1186/s12891-024-07473-3.

引用本文的文献

1
Sleep Characteristics in Individuals with Ehlers-Danlos Syndrome.埃勒斯-当洛综合征患者的睡眠特征
Med Sci (Basel). 2025 Jun 27;13(3):85. doi: 10.3390/medsci13030085.
2
Priority Musculoskeletal Health Research Questions for People With Generalized Joint Hypermobility: An International Delphi Study.广泛性关节过度活动人群的优先肌肉骨骼健康研究问题:一项国际德尔菲研究
Arthritis Care Res (Hoboken). 2025 Jun;77(6):792-800. doi: 10.1002/acr.25501. Epub 2025 Feb 17.
3
The biopsychosocial impact of hypermobility spectrum disorders in adults: a scoping review.

本文引用的文献

1
A validity and reliability study of the Turkish Checklist Individual Strength (CIS) questionnaire in musculoskeletal physical therapy patients.土耳其肌肉骨骼物理治疗患者个体力量检查表(CIS)问卷的有效性和可靠性研究。
Physiother Theory Pract. 2012 Nov;28(8):624-32. doi: 10.3109/09593985.2011.654321. Epub 2012 Feb 10.
2
Symptom and joint mobility progression in the joint hypermobility syndrome (Ehlers-Danlos syndrome, hypermobility type).关节过度活动综合征(Ehlers-Danlos 综合征,过度活动型)的症状和关节活动度进展。
Clin Exp Rheumatol. 2011 Nov-Dec;29(6):998-1005.
3
Association between psychopathological factors and joint hypermobility syndrome in a group of undergraduates from a French university.
成人易发性运动障碍谱相关的生物心理社会影响:范围综述。
Rheumatol Int. 2023 Jun;43(6):985-1014. doi: 10.1007/s00296-023-05298-2. Epub 2023 Mar 10.
4
Connecting brain and body: Transdiagnostic relevance of connective tissue variants to neuropsychiatric symptom expression.连接大脑与身体:结缔组织变异对神经精神症状表达的跨诊断相关性
World J Psychiatry. 2021 Oct 19;11(10):805-820. doi: 10.5498/wjp.v11.i10.805.
5
Psychosocial Influence of Ehlers-Danlos Syndrome in Daily Life of Patients: A Qualitative Study.Ehlers-Danlos 综合征患者日常生活中的心理社会影响:一项定性研究。
Int J Environ Res Public Health. 2020 Sep 3;17(17):6425. doi: 10.3390/ijerph17176425.
6
Custom-Made Foot Orthoses Reduce Pain and Fatigue in Patients with Ehlers-Danlos Syndrome. A Pilot Study.定制足部矫形器可减轻埃勒斯-当洛斯综合征患者的疼痛和疲劳:一项初步研究。
Int J Environ Res Public Health. 2020 Feb 20;17(4):1359. doi: 10.3390/ijerph17041359.
7
Quantitative measures of tissue mechanics to detect hypermobile Ehlers-Danlos syndrome and hypermobility syndrome disorders: a systematic review.定量测量组织力学以检测过度活动型埃勒斯-当洛斯综合征和过度活动综合征障碍:系统评价。
Clin Rheumatol. 2020 Mar;39(3):715-725. doi: 10.1007/s10067-020-04939-2. Epub 2020 Jan 18.
8
Pain and sleep quality in children with non-vascular Ehlers-Danlos syndromes.非血管性埃勒斯-当洛综合征患儿的疼痛与睡眠质量
Am J Med Genet A. 2018 Sep;176(9):1858-1864. doi: 10.1002/ajmg.a.40371. Epub 2018 Sep 4.
9
Prevalence, injury rate and, symptom frequency in generalized joint laxity and joint hypermobility syndrome in a "healthy" college population.“健康”大学生群体中全身关节松弛和关节活动过度综合征的患病率、损伤率及症状发生频率
Clin Rheumatol. 2016 Apr;35(4):1029-39. doi: 10.1007/s10067-015-2951-9. Epub 2015 May 1.
大学生群体中心理病理因素与关节过度活动综合征的相关性研究。
Int J Psychiatry Med. 2011;41(2):187-201. doi: 10.2190/PM.41.2.g.
4
Joint hypermobility syndrome: problems that require psychological intervention.关节过度活动综合征:需要心理干预的问题。
Rheumatol Int. 2011 Sep;31(9):1131-6. doi: 10.1007/s00296-011-1839-5. Epub 2011 Mar 4.
5
Pain in ehlers-danlos syndrome is common, severe, and associated with functional impairment.埃勒斯-当洛斯综合征常伴有疼痛,且疼痛剧烈,可导致功能障碍。
J Pain Symptom Manage. 2010 Sep;40(3):370-8. doi: 10.1016/j.jpainsymman.2009.12.026. Epub 2010 Jun 25.
6
Quality of life in the classic and hypermobility types of Ehlers-Danlos syndrome [corrected].经典型和关节活动过度型埃勒斯-当洛综合征的生活质量[已修正]
Ann Neurol. 2010 Jan;67(1):145-6; author reply 146-7. doi: 10.1002/ana.21934.
7
Musculoskeletal complaints, physical activity and health-related quality of life among patients with the Ehlers-Danlos syndrome hypermobility type.肌肉骨骼抱怨、身体活动和 Ehlers-Danlos 综合征高活动型患者的健康相关生活质量。
Disabil Rehabil. 2010;32(16):1339-45. doi: 10.3109/09638280903514739.
8
Fatigue is a frequent and clinically relevant problem in Ehlers-Danlos Syndrome.疲劳是埃勒斯-当洛斯综合征中常见且具有临床相关性的问题。
Semin Arthritis Rheum. 2010 Dec;40(3):267-74. doi: 10.1016/j.semarthrit.2009.08.003. Epub 2009 Oct 30.
9
The lack of clinical distinction between the hypermobility type of Ehlers-Danlos syndrome and the joint hypermobility syndrome (a.k.a. hypermobility syndrome).埃勒斯-当洛综合征的关节过度活动型与关节过度活动综合征(又称活动过度综合征)之间缺乏临床鉴别。
Am J Med Genet A. 2009 Nov;149A(11):2368-70. doi: 10.1002/ajmg.a.33070.
10
Persistent severe fatigue in patients with rheumatoid arthritis.类风湿关节炎患者持续存在的严重疲劳
J Clin Nurs. 2007 Nov;16(11C):377-83. doi: 10.1111/j.1365-2702.2007.02082.x.