Puig Lluis, Kirby Brian, Mallbris Lotus, Strohal Robert
Department of Dermatology, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Sant Antoni Maria Claret 167, 08025 Barcelona, Spain.
St Vincent's University Hospital, Elm Park, Dublin, Ireland.
Eur J Dermatol. 2014 May-Jun;24(3):305-11. doi: 10.1684/ejd.2014.2299.
Psoriasis is increasingly associated with a range of co-morbid diseases and risk factors. Patients with co-morbidities are more likely to need hospitalisation for non-dermatological conditions, and incur greater total costs than those without co-morbidities. A literature review was conducted on two of the most common co-morbidities of psoriasis (cardiovascular (CV) and psychological co-morbidities), to establish their incidence and impact and to raise awareness of unanswered questions and highlight knowledge gaps. A large number of small controlled or cross-sectional studies report increased prevalence of cardiometabolic and psychological co-morbidities in psoriasis patients. A number of large cohort studies documented the incidence of various cardiometabolic co-morbidities. Severe psoriasis is associated with increased mortality, and the most common cause of death is CV disease. Studies on the management of co-morbidities and their impact on psoriasis treatment are scarce. Many questions on the co-morbidities of psoriasis remain to be answered.
银屑病越来越多地与一系列共病疾病和风险因素相关联。患有共病的患者因非皮肤病状况而更有可能需要住院治疗，并且比没有共病的患者产生更高的总费用。针对银屑病的两种最常见共病（心血管共病和心理共病）进行了一项文献综述，以确定它们的发病率和影响，并提高对未解决问题的认识以及突出知识空白。大量小型对照研究或横断面研究报告称，银屑病患者中心血管代谢和心理共病的患病率有所增加。一些大型队列研究记录了各种心血管代谢共病的发病率。重度银屑病与死亡率增加相关，最常见的死亡原因是心血管疾病。关于共病管理及其对银屑病治疗影响的研究很少。关于银屑病共病仍有许多问题有待解答。
