Sherwani Rana, Akhtar Kafil, Ahmad Murad, Hasan Abrar
Departments of Pathology and.
Ear, Nose & Throat (ENT), Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh(U.P), India.
Clin Pract. 2011 Jul 1;1(3):e58. doi: 10.4081/cp.2011.e58.
A rare case of acinic cell carcinoma of minor salivary gland with cervical lymph node metastasis in a 50-year-old man is reported and the literature regarding this type of tumor is reviewed. These tumors arise from either an intercalated duct stem cell or the reserve cell of the salivary gland terminal tubule but not from both simultaneously. Rarely these neoplasms arise from more mature acinar cells. It is clear that these tumors behave ominously. The 25 year determinate survival rate is 50%, with a 20% incidence of metastasis. Surgical excision is the treatment of choice. Radiotherapy, especially neutron therapy, has a place in the treatment of this tumor but the role of chemotherapy is not exactly known at this time.
本文报道了一例50岁男性小涎腺腺泡细胞癌伴颈部淋巴结转移的罕见病例，并对有关此类肿瘤的文献进行了综述。这些肿瘤起源于闰管干细胞或涎腺终末小管的储备细胞，但不会同时起源于两者。这些肿瘤很少起源于更成熟的腺泡细胞。显然，这些肿瘤预后不佳。25年的确定生存率为50%，转移发生率为20%。手术切除是首选治疗方法。放射治疗，尤其是中子治疗，在该肿瘤的治疗中占有一席之地，但化疗目前的确切作用尚不清楚。
