Department of Biomedical Engineering, The City College of New York, City University of New York, New York, NY, USA.
Department of Biomedical Engineering, The City College of New York, City University of New York, New York, NY, USA.
Brain Stimul. 2014 Jul-Aug;7(4):521-4. doi: 10.1016/j.brs.2014.03.009. Epub 2014 Mar 30.
Computational models of brain current flow during transcranial electrical stimulation (tES), including transcranial direct current stimulation (tDCS) and transcranial alternating current stimulation (tACS), are increasingly used to understand and optimize clinical trials. We propose that broad dissemination requires a simple graphical user interface (GUI) software that allows users to explore and design montages in real-time, based on their own clinical/experimental experience and objectives. We introduce two complimentary open-source platforms for this purpose: BONSAI and SPHERES. BONSAI is a web (cloud) based application (available at neuralengr.com/bonsai) that can be accessed through any flash-supported browser interface. SPHERES (available at neuralengr.com/spheres) is a stand-alone GUI application that allow consideration of arbitrary montages on a concentric sphere model by leveraging an analytical solution. These open-source tES modeling platforms are designed go be upgraded and enhanced. Trade-offs between open-access approaches that balance ease of access, speed, and flexibility are discussed.
用于经颅电刺激（tES），包括经颅直流电刺激（tDCS）和经颅交流电刺激（tACS）的脑电流流动的计算模型，越来越多地被用于理解和优化临床试验。我们提出，广泛传播需要一个简单的图形用户界面（GUI）软件，允许用户根据自己的临床/实验经验和目标实时探索和设计组合。为此，我们引入了两个互补的开源平台：BONSAI 和 SPHERES。BONSAI 是一个基于网络（云）的应用程序（可在 neuralengr.com/bonsai 上访问），可以通过任何支持 flash 的浏览器界面进行访问。SPHERES（可在 neuralengr.com/spheres 上访问）是一个独立的 GUI 应用程序，允许通过利用解析解在同心球模型上考虑任意组合。这些开源 tES 建模平台旨在进行升级和增强。讨论了在易于访问、速度和灵活性之间取得平衡的开放访问方法的权衡。
