Bottini Paula V, Martinez Mayara H M, Garlipp Célia R
Clin Lab. 2014;60(4):693-7. doi: 10.7754/clin.lab.2013.130725.
Urinalysis is a high demand procedure, with a large amount of manual labor and poorly standardized. Recently a new walk-away automated urine analyzer has been introduced. The aim of this study was to evaluate the performance of UriSed as an alternative to the microscopic analysis of urine samples.
Four hundred mid-stream urine samples from patients with several clinical conditions were analyzed by bright field microscopy and by UriSed. The validation protocol included studies of precision, carryover, and comparison with the gold standard microscopy.
Our data showed that UriSed is a precise method. Repeatability and reproducibility ranged from 8 to 15%. Carryover was negligible. All the elements showed good agreement between both methods, with an extremely high correlation between the erythrocyte and leukocyte counts (r > 0.95) CONCLUSIONS: UriSed is a precise and accurate alternative to microscopy that allows a better workflow and may significantly improve turnaround time.
尿液分析是一项需求很高的检查项目，存在大量体力劳动且标准化程度低。最近引入了一种新型的无需人工操作的自动尿液分析仪。本研究的目的是评估UriSed作为尿液样本显微镜检查替代方法的性能。
采用明场显微镜检查和UriSed对400例患有多种临床疾病患者的中段尿样本进行分析。验证方案包括精密度、残留研究以及与金标准显微镜检查的比较。
我们的数据表明UriSed是一种精确的方法。重复性和再现性范围为8%至15%。残留可忽略不计。两种方法对所有成分的检测结果均显示出良好的一致性，红细胞和白细胞计数之间具有极高的相关性（r>0.95）。结论：UriSed是一种精确且准确的显微镜检查替代方法，可实现更好的工作流程，并可能显著缩短周转时间。
