Fazzino Tera L, Rose Gail L, Burt Keith B, Helzer John E
Department of Psychology, University of Vermont, 2 Colchester Avenue, Burlington, VT 05401, USA; Department of Psychiatry, University of Vermont, 1 South Prospect Street, Burlington, VT 05401, USA.
Department of Psychiatry, University of Vermont, 1 South Prospect Street, Burlington, VT 05401, USA.
Drug Alcohol Depend. 2014 Aug 1;141:39-43. doi: 10.1016/j.drugalcdep.2014.05.004. Epub 2014 May 17.
For the DSM-5-defined alcohol use disorder (AUD) diagnosis, a tri-categorized scale that designates mild, moderate, and severe AUD was selected over a fully dimensional scale to represent AUD severity. The purpose of this study was to test whether the DSM-5-defined AUD severity measure was as proficient a predictor of alcohol use following a brief intervention, compared to a fully dimensional scale.
Heavy drinking primary care patients (N=246) received a physician-delivered brief intervention (BI), and then reported daily alcohol consumption for six months using an Interactive Voice Response (IVR) system. The dimensional AUD measure we constructed was a summation of all AUD criteria met at baseline (mean=6.5; SD=2.5). A multi-model inference technique was used to determine whether the DSM-5 tri-categorized severity measure or a dimensional approach would provide a more precise prediction of change in weekly alcohol consumption following a BI.
The Akaike information criterion (AIC) for the dimensional AUD model (AIC=7623.88) was four points lower than the tri-categorized model (AIC=7627.88) and weight of evidence calculations indicated there was 88% likelihood the dimensional model was the better approximating model. The dimensional model significantly predicted change in alcohol consumption (p=.04) whereas the DSM-5 tri-categorized model did not.
A dimensional AUD measure was superior, detecting treatment effects that were not apparent with tri-categorized severity model as defined by the DSM-5. We recommend using a dimensional measure for determining AUD severity.
对于DSM - 5定义的酒精使用障碍(AUD)诊断,选用了一个将AUD分为轻度、中度和重度的三分类量表,而非全维度量表来表示AUD的严重程度。本研究的目的是检验与全维度量表相比,DSM - 5定义的AUD严重程度测量指标在短暂干预后对酒精使用的预测能力是否同样出色。
重度饮酒的初级保健患者(N = 246)接受了医生提供的短暂干预(BI),然后使用交互式语音应答(IVR)系统报告六个月内的每日酒精摄入量。我们构建的维度AUD测量指标是基线时满足的所有AUD标准的总和(均值 = 6.5;标准差 = 2.5)。采用多模型推断技术来确定DSM - 5三分类严重程度测量指标或维度方法是否能更精确地预测短暂干预后每周酒精摄入量的变化。
维度AUD模型的赤池信息准则(AIC)(AIC = 7623.88)比三分类模型(AIC = 7627.88)低4分,证据权重计算表明维度模型有88%的可能性是更好的近似模型。维度模型显著预测了酒精摄入量的变化(p = 0.04),而DSM - 5三分类模型则没有。
维度AUD测量指标更具优势,能够检测出DSM - 5定义的三分类严重程度模型未显示出的治疗效果。我们建议使用维度测量指标来确定AUD的严重程度。