从斜叶厚皮香的枝叶中分离得到的两个新的羊毛甾烷三萜。

Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou 571158, Hainan, China.

Molecules. 2014 Jun 6;19(6):7621-8. doi: 10.3390/molecules19067621.

Two new lanostane triterpenoids, 20-hydroxyeuphorbol-7-one (1) and 15α-hydroxyeuphorbol-7,11-dione (2), together with four known triterpenoids, euphorbol-7-one (3), friedelin (4), stigmast-4-ene-6α-ol-3-one (5), stigmasta-4-en-3,6-dione (6), were isolated from ethanol extract of the branches and leaves of Polyalthia obliqua. The structures of 1 and 2 were elucidated on the basis of extensive spectroscopic analysis and comparisons with related known compounds. Antibacterial activities of two new compounds and four known compounds were tested.

从斜叶厚皮香的枝叶乙醇提取物中分离得到两个新的羊毛甾烷型三萜化合物 20-羟基-表羊毛甾-7-酮（1）和 15α-羟基-表羊毛甾-7,11-二酮（2），以及四个已知的三萜化合物，即羊毛甾-7-酮（3）、羽扇豆醇（4）、豆甾-4-烯-6α-醇-3-酮（5）和豆甾-4-烯-3,6-二酮（6）。通过广泛的光谱分析和与相关已知化合物的比较，确定了 1 和 2 的结构。测试了两个新化合物和四个已知化合物的抗菌活性。