Neuroscience Research Centre, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran.
Psychiatry Clin Neurosci. 2014 Jun;68(6):410-7. doi: 10.1111/pcn.12148. Epub 2014 Feb 19.
Deficits in mental imagery ability have been reported in patients with schizophrenia. However, there is scarce evidence about the correlation between impairment in mental rotation and other cognitive deficits in the patients. The aim of this study was to assess mental rotation ability, along with other measures of cognitive function in patients with schizophrenia.
The performance of 29 patients with schizophrenia was compared with 29 healthy controls. Mental rotation was measured with the Hand Rotation Task, and cognitive functions were measured with the Brief Assessment of Cognition in Schizophrenia (BACS).
On Hand Rotation Task, the patients were significantly slower and less accurate compared to controls. Moreover, mental rotation accuracy was significantly correlated with all the BACS domains except verbal memory. In multiple regression analysis, the two BACS subscales, Tower of London and Symbol Coding tasks, were significant predictors and accounted for 41% of the variance in accuracy in the patients.
These results support previous findings showing dysfunction of the posterior parietal cortex in schizophrenia, which is involved in general mental rotation, as well as other cognitive processes.
有研究报道精神分裂症患者存在心理意象能力缺陷。然而，关于精神分裂症患者的心理旋转损伤与其他认知缺陷之间的相关性，证据还很少。本研究旨在评估精神分裂症患者的心理旋转能力以及其他认知功能。
将 29 名精神分裂症患者的表现与 29 名健康对照者进行比较。使用 Hand Rotation Task 测量心理旋转能力，使用 Brief Assessment of Cognition in Schizophrenia (BACS) 测量认知功能。
在 Hand Rotation Task 上，患者的反应速度明显慢于对照组，准确性也明显低于对照组。此外，心理旋转的准确性与 BACS 所有领域均显著相关，除了言语记忆。在多元回归分析中，Tower of London 和 Symbol Coding 两个 BACS 子量表是显著的预测因子，解释了患者准确性变异的 41%。
这些结果支持了先前的研究结果，表明精神分裂症患者的后顶叶皮层功能障碍与一般心理旋转以及其他认知过程有关。
