Nedime Sahinoglu-Keskek, MD, Department of Ophthalmology, Numune Training and Research Hospital, Adana, Turkey.
Sakir Ozgur Keskek, MD, Department of Internal Medicine, Numune Training and Research Hospital, Adana, Turkey.
Pak J Med Sci. 2014 May;30(3):477-82. doi: 10.12669/pjms.303.4514.
The aim of this study was to investigate the association between intraocular pressure and metabolic syndrome by comparing central corneal thicknesses.
One hundred sixty-two subjects were enrolled in this cross-sectional study, with 89 subjects in a metabolic syndrome group and 73 subjects in a control group. Ophthalmological examinations, including intraocular pressure and central corneal thickness measurements, were performed on each subject. Serum fasting glucose, triglyceride and HDL cholesterol levels were measured, and waist circumference, systolic and diastolic blood pressure of all patients were recorded.
Participants with metabolic syndrome had a significantly higher intraocular pressure than those without metabolic syndrome (p = 0.008), and there was no statistically significant difference between the central corneal thicknesses of the two groups (p = 0.553). Most of the metabolic syndrome components were associated with higher intraocular pressure (p < 0.05).
There is a relationship between metabolic syndrome and intraocular pressure, but no association between metabolic syndrome and central corneal thicknesses. Intraocular pressure is affected by central corneal thicknesses, and intraocular pressure is used to correct according to the central corneal thicknesses measurement. To our knowledge, this is the first study that determines the positive relationship between metabolic syndrome and intraocular pressure by comparing the central corneal thicknesses of the groups.
本研究旨在通过比较中央角膜厚度来探讨眼压与代谢综合征之间的关系。
本横断面研究纳入了 162 名受试者，其中 89 名为代谢综合征组，73 名为对照组。对每位受试者进行眼科检查，包括眼压和中央角膜厚度测量。检测所有患者的血清空腹血糖、甘油三酯和高密度脂蛋白胆固醇水平，并记录其腰围、收缩压和舒张压。
患有代谢综合征的参与者的眼压明显高于没有代谢综合征的参与者（p = 0.008），两组的中央角膜厚度无统计学差异（p = 0.553）。大多数代谢综合征成分与较高的眼压相关（p < 0.05）。
代谢综合征与眼压之间存在关系，但代谢综合征与中央角膜厚度之间没有关系。眼压受中央角膜厚度的影响，根据中央角膜厚度测量值进行眼压校正。据我们所知，这是第一项通过比较两组的中央角膜厚度来确定代谢综合征与眼压之间正相关关系的研究。
