Servei de RMN and Departament de Química, Universitat Autònoma de Barcelona, 08193 Bellaterra (Spain).
Angew Chem Int Ed Engl. 2014 Aug 4;53(32):8379-82. doi: 10.1002/anie.201404136. Epub 2014 Jun 24.
A general NMR approach to provide pure in-phase (PIP) multiplets in heteronuclear correlation experiments is described. The implementation of a zero-quantum filter efficiently suppresses any unwanted anti-phase contributions that usually distort the multiplet pattern of cross-peaks and can hamper their analysis. The clean pattern obtained in PIP-HSQMBC experiments is suitable for a direct extraction of coupling constants in resolved signals, for a peak-fitting process from a reference signal, and for the application of the IPAP technique in non-resolved multiplets.
本文描述了一种通用的 NMR 方法，可在异核相关实验中提供纯同相（PIP）多重峰。通过实施零量子滤波器，可以有效地抑制通常会扭曲交叉峰多重峰图案并可能阻碍其分析的任何不需要的反相贡献。在 PIP-HSQMBC 实验中获得的清晰图案适用于从分辨信号中直接提取耦合常数、从参考信号进行峰拟合过程以及在非分辨多重峰中应用 IPAP 技术。
