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关于修订后的霉菌毒素及其他形式霉菌毒素(包括“隐蔽”霉菌毒素)的全面定义提案。

Proposal of a comprehensive definition of modified and other forms of mycotoxins including "masked" mycotoxins.

作者信息

Rychlik Michael, Humpf Hans-Ulrich, Marko Doris, Dänicke Sven, Mally Angela, Berthiller Franz, Klaffke Horst, Lorenz Nicole

机构信息

Chair of Analytical Food Chemistry, Technische Universität München, Alte Akademie 10, 85354, Freising, Germany.

出版信息

Mycotoxin Res. 2014 Nov;30(4):197-205. doi: 10.1007/s12550-014-0203-5. Epub 2014 Jun 26.

Abstract

As the term "masked mycotoxins" encompasses only conjugated mycotoxins generated by plants and no other possible forms of mycotoxins and their modifications, we hereby propose for all these forms a systematic definition consisting of four hierarchic levels. The highest level differentiates the free and unmodified forms of mycotoxins from those being matrix-associated and from those being modified in their chemical structure. The following lower levels further differentiate, in particular, "modified mycotoxins" into "biologically modified" and "chemically modified" with all variations of metabolites of the former and dividing the latter into "thermally formed" and "non-thermally formed" ones. To harmonize future scientific wording and subsequent legislation, we suggest that the term "modified mycotoxins" should be used in the future and the term "masked mycotoxins" to be kept for the fraction of biologically modified mycotoxins that were conjugated by plants.

摘要

由于“隐蔽性霉菌毒素”仅涵盖植物产生的共轭霉菌毒素,不包括其他任何可能形式的霉菌毒素及其修饰产物,因此我们在此为所有这些形式提出一个由四个层次级别组成的系统定义。最高级别将霉菌毒素的游离和未修饰形式与那些与基质相关的形式以及化学结构发生修饰的形式区分开来。接下来的较低级别进一步区分,特别是将“修饰霉菌毒素”分为“生物修饰”和“化学修饰”,前者包括所有代谢产物变体,后者分为“热形成”和“非热形成”两类。为了统一未来的科学术语和后续立法,我们建议未来使用“修饰霉菌毒素”一词,而“隐蔽性霉菌毒素”一词应保留用于植物共轭的生物修饰霉菌毒素部分。

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