Obaseki Daniel O, Kolawole Babatope A, Gomerep Simji S, Obaseki Josephine E, Abidoye Ibukun A, Ikem Rosemary T, Erhabor Gregory E
Department of Medicine, Obafemi Awolowo University, Ile-Ife, Nigeria.
Department of Medicine, Jos University Teaching Hospital, Jos, Nigeria.
Niger Med J. 2014 Jan;55(1):24-8. doi: 10.4103/0300-1652.128154.
Obstructive sleep apnea (OSA) and Diabetes Mellitus (DM) are growing health challenges worldwide. However, the relation of OSA with type 2 diabetes is not well understood in developing countries. This study described the prevalence and predictors of OSA in type 2 DM patients using a screening questionnaire.
Patients aged 40years and above with type 2 diabetes mellitus were recruited into the study consecutively from the outpatient clinics of a university hospital. They were all administered the Berlin questionnaire and the Epworth sleepiness scale (ESS) to assess the risk of OSA and the tendency to doze off, respectively. Anthropometric details like height, weight and body mass index (BMI) were measured and short-term glycaemic control was determined using fasting blood glucose.
A total of 117 patients with type 2 diabetes mellitus were recruited into the study. The mean (SD) age, height and BMI was 63 years (11), 160 cm (9) and 27.5 kg/ m(2) (5.7), respectively. Twenty-seven percent of the respondents had a high risk for OSA and 22% had excessive daytime sleepiness denoted by ESS score above 10. In addition, the regression model showed that for every 1 cm increase in neck circumference, there is a 56% independent increase in the likelihood of high risk of OSA after adjusting for age, sex, BMI, waist, hip circumferences and blood glucose.
Our study shows a substantial proportion of patients with type 2 diabetes may have OSA, the key predictor being neck circumference after controlling for obesity.
阻塞性睡眠呼吸暂停(OSA)和糖尿病(DM)是全球范围内日益严峻的健康挑战。然而,在发展中国家,OSA与2型糖尿病之间的关系尚未得到充分理解。本研究使用筛查问卷描述了2型糖尿病患者中OSA的患病率及预测因素。
从一所大学医院的门诊连续招募年龄在40岁及以上的2型糖尿病患者。对他们均进行柏林问卷和爱泼华嗜睡量表(ESS)评估,分别以评估OSA风险和打瞌睡倾向。测量身高、体重和体重指数(BMI)等人体测量细节,并使用空腹血糖测定短期血糖控制情况。
共有117名2型糖尿病患者纳入本研究。平均(标准差)年龄、身高和BMI分别为63岁(11)、160厘米(9)和27.5千克/平方米(5.7)。27%的受访者有患OSA的高风险,22%的人存在日间过度嗜睡,即ESS评分高于10分。此外,回归模型显示,在调整年龄、性别、BMI、腰围、臀围和血糖后,颈围每增加1厘米,患OSA高风险的可能性独立增加56%。
我们的研究表明,相当一部分2型糖尿病患者可能患有OSA,在控制肥胖后,关键预测因素是颈围。