从真菌里克拟层孔菌子实体中分离得到的四种新倍半萜类化合物。
Four new sesquiterpenoids from fruiting bodies of the fungus Inonotus rickii.
作者信息
Chen He-Ping, Dong Wen-Bin, Feng Tao, Yin Xia, Li Zheng-Hui, Dong Ze-Jun, Li Yan, Liu Ji-Kai
机构信息
a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences , Kunming 650201 , China.
出版信息
J Asian Nat Prod Res. 2014;16(6):581-6. doi: 10.1080/10286020.2014.925451. Epub 2014 Jun 30.
Three new bisabolane sesquiterpenoids, inonotic acid A (1), 3-O-formyl inonotic acid A (2), inonotic acid B (3), and one new drimane sesquiterpenoid 3α,6β-dihydroxycinnamolide (4), were isolated from the fruiting bodies of mushroom Inonotus rickii. Their structures were elucidated by means of extensive spectroscopic methods. Compound 4 had moderate inhibitory activity on human colon cancer SW480 (IC50 = 20.4 μmol).
从蘑菇里克拟层孔菌（Inonotus rickii）的子实体中分离出三种新的没药烷倍半萜类化合物，异诺托酸A（1）、3 - O - 甲酰基异诺托酸A（2）、异诺托酸B（3），以及一种新的杜松烷倍半萜类化合物3α,6β - 二羟基肉桂酰内酯（4）。通过广泛的光谱方法阐明了它们的结构。化合物4对人结肠癌SW480具有中等抑制活性（IC50 = 20.4 μmol）。
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