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用于扫描模式X射线相衬成像的倾斜光栅方法。

Tilted-grating approach for scanning-mode X-ray phase contrast imaging.

作者信息

Arboleda Carolina, Wang Zhentian, Stampanoni Marco

出版信息

Opt Express. 2014 Jun 30;22(13):15447-58. doi: 10.1364/OE.22.015447.

DOI:10.1364/OE.22.015447
PMID:24977804
Abstract

Among the existent X-ray phase-contrast modalities, grating interferometry appears as a very promising technique for commercial applications, since it is compatible with conventional X-ray tubes and is robust from a mechanical point of view. However, since applications such as medical imaging and homeland security demand covering a considerable field of view, the fabrication of large-area gratings, which is known to be challenging and expensive, would be needed. A scanning setup is a good solution for this issue, because it uses cheaper line instead of large-area 2D detectors and, therefore, would require smaller gratings. In such a setup, the phase-retrieval using the conventional phase-stepping approach would be very slow, so having a faster method to record the signals becomes fundamental. To tackle this problem, we present a scanning-mode grating interferometer design, in which a grating is tilted to form Moiré fringes perpendicular to the grating lines. The sample is then translated along the fringes, so each line detector records a different phase step for each slice of the sample. This new approach was tested both in a simulated scenario and in an experimental setting, and its performance was quantitatively satisfactory compared to the traditional phase-stepping method and another existing scanning-mode technique.

摘要

在现有的X射线相衬成像技术中,光栅干涉术似乎是一种非常有前景的商业应用技术,因为它与传统X射线管兼容,并且从机械角度来看很坚固。然而,由于医学成像和国土安全等应用需要覆盖相当大的视场,因此需要制造大面积光栅,而这已知具有挑战性且成本高昂。扫描装置是解决此问题的一个好办法,因为它使用更便宜的线探测器而非大面积二维探测器,因此所需的光栅尺寸更小。在这样的装置中,使用传统相移方法进行相位恢复会非常缓慢,所以拥有一种更快的信号记录方法变得至关重要。为了解决这个问题,我们提出了一种扫描模式光栅干涉仪设计,其中光栅倾斜以形成垂直于光栅线的莫尔条纹。然后将样品沿着条纹平移,这样每个线探测器为样品的每个切片记录不同的相移步长。这种新方法在模拟场景和实验环境中都进行了测试,与传统相移方法和另一种现有的扫描模式技术相比,其性能在定量上令人满意。

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